Research Training in Pediatric Cardiology

描述（由申请人提供）：本申请要求继续支持资助T32 HL 007710，目的是增加专注于儿科心血管疾病的成功临床和翻译研究者的数量和质量。在这项补助金的头14年里，35名受训人员的研究生产力和学术事业发展都很可观。在这个竞争性的更新申请中，我们描述了培训和指导儿科心脏病学研究人员的计划，这些研究人员以患者为导向，专注于儿科心脏病学的重大挑战。该计划为儿科心脏病学（MD）研究员提供两种模式研究培训途径：临床研究者和翻译临床医生科学家途径。每个受训者将有一个主要的lentor和指导团队，由临床和基础科学导师组成，从而增加了思想和经验的广度，以提高职业发展。该计划确定并促进每个学员理想的个性化培训目标，以最大限度地提高他或她的机会，成为一个富有成效的学术研究者，具有可持续的竞争力，为校外研究支持。MUSC的科学和计划资源被整合到这个研究培训计划中，包括作为NHLBI儿科心脏网络的主要临床中心参与;蓬勃发展的临床儿科心脏病学奖学金培训计划;儿科心脏病学和儿科心脏手术的合作临床教师，拥有广泛的出版物，研究资金和参与多机构研究的记录;在心血管发育生物学，心脏形态发生，细胞外基质生物学，心脏肥大，重塑，伤口愈合，细胞修复，干细胞生物学，组织工程，生物工程和假体设备开发方面的特殊师资力量;通过NIH资助的CTSA计划，在临床研究方法方面提供广泛的教学培训机会;一个完善的，成功的临床研究硕士学位课程;临床和基础科学研究环境与证明少数民族招聘成功;大量的机构承诺;达比儿童研究所;和NIH/NCRR中心的生物医学研究卓越（COBRE）在心血管发育生物学。一个综合的多年评价计划将记录和评估方案目标和目的的实现程度，并为持续改进和提高提供关键信息。

DESCRIPTION (provided by applicant): This application requests continued support of grant T32 HL 007710 with the goal of increasing the number and quality of successful clinical and translational investigators focused on pediatric cardiovascular disease. The research productivity and academic career advancement of the 35 trainees supported during the first 14 years of this grant are substantial. In this competing renewal application, we describe plans for training and mentoring pediatric cardiology research fellows in patient-oriented and translational research focused on significant challenges in pediatric cardiology. The program has two model research training pathways for pediatric cardiology (MD) fellows: the Clinical Investigator and Translational Clinician Scientist Pathways. Each trainee will have a Primary l\/ lentor and Mentoring Team composed of both clinical and basic science mentors, thereby increasing the breadth of ideas and experience available to enhance career development. The program identifies and promotes desirable individualized training goals for each trainee in order to maximize his or her opportunity to become a productive academic investigator with sustainable competitiveness for extramural research support. Scientific and programmatic resources at MUSC that are integrated into this research training program include participation as a primary Clinical Center in the NHLBI Pediatric Heart Network; a thriving clinical pediatric cardiology fellowship training program; a collaborative clinical faculty in pediatric cardiology and pediatric cardiac surgery with an extensive track record of publications, research funding and participation in multi-institutional studies; exceptional faculty strengths in cardiovascular developmental biology, cardiac morphogenesis, extracellular matrix biology, cardiac hypertrophy, remodeling, wound healing, cellular repair, stem cell biology, tissue engineering, bioengineering and prosthetic device development; a wide array of didactic training opportunities in clinical research methodology through the NIH-funded CTSA program; a well-developed, successful Master of Science in Clinical Research degree program; clinical and basic science research environments with proven minority recruitment success; substantial institutional commitment; the Darby Children's Research Institute; and an NIH/NCRR Center of Biomedical Research Excellence (COBRE) in cardiovascular developmental biology. An integrated multi-year evaluation plan will document and assess the extent to which program goals and objectives are met and provide critical information for ongoing improvement and enhancement.