Histopathology Core

NEI的组织病理学核心是CLIA许可的机构，致力于支持NEI和NIH其他合作机构的患者护理、视力研究和使命。这包括对手术中取出的人体组织(主要是眼组织)进行处理，并在尸检时收集。核心的组织，切片和染色载玻片的光镜和/或透射电子显微镜。该中心还对眼液进行细胞学检查。组织病理学核心为临床分部和NEI内壁研究计划下的所有NEI实验室以及其他NIH研究所提供服务，这些研究所进行涉及眼部和相关组织和液体的研究。此外，该中心还接收NIH(美国和国外)以外的临床医生和研究人员提交的用于诊断、咨询或合作的临床和实验标本。 在2014财年，组织病理学核心收到和处理了大约4044个标本，并产生了5100多张染色的玻片。此外，该实验室还处理了送往超微结构的病例材料，产生了3717张电子显微镜图像。本财政年度还收到并处理了65例临床病例。患者标本制作了1722张组织切片和115张电子显微镜图像。有20多份出版物包括核心所开展的工作。虽然我们大约95%的工作都致力于NEI的职责，但组织病理学核心也为来自NIH内外的其他研究所、大学、医生和研究人员的研究项目提供服务。该核心遵循国家卫生研究院内部研究项目的研究指导方针和国家卫生研究院制定的其他标准。

The Histopathology Core of the NEI, a CLIA licensed facility, is devoted to supporting the patient care, vision research, and mission of the NEI and other collaborative institutes at the NIH. This consists of processing human tissues (mainly ocular tissues) removed in surgeries and collected at autopsies. The Core grosses the tissues, sections and stains slides for light and/or transmission electron microscopy. The Core also performs cytology examination of ocular fluids. The Histopathology Core serves the Clinical Branch and all NEI laboratories under the NEI Intramural Research Program, as well as other NIH institutes, which conduct research involving ocular and related tissues and fluids. In addition, the Core receives clinical and experimental specimens submitted by clinicians and investigators outside NIH (USA and abroad) for diagnosis, consultation or collaboration. During FY14, the Histopathology Core received and processed approximately 4044 specimens and yielded over 5100 slides stained. Additionally, the laboratory processed case materials sent for ultrastructure, which produced 3717 electron microscopic images. This fiscal year, 65 clinical cases were also received and processed. The patient specimens produced 1722 histological slides and 115 electronic microscopic images. There are over 20 publications that include work performed by the Core. Although about 95% of our effort is devoted to NEI duties, the Histopathology Core also performs services for research projects from other institutes, universities, physicians and researchers inside and outside the NIH. The core follows the guidelines for the conduct of research in the intramural research program at the NIH and other standards set by the NIH.