BioInfo Core NINDS Institutional Center Core Grants to Support Neuroscience Res

摘要和相关性 生物信息学核心代表了这次中心赠款更新的新倡议，取代了表达分析(Affyrrietrix)的核心设施，后者现在是自我维持的。拟议的生物信息学核心将通过为神经科学家提供专门的生物信息学家，促进大规模并行测序(MPS)技术的使用。该核心还将作为NINDS资助的和其他北卡罗来纳大学神经科学教员的专门知识宝库，特别是在设计MPS实验、数据分析和使用北卡罗来纳大学教堂山现有MPS基础设施方面。由于卡罗莱纳发育障碍研究所(COLD)的神经科学家也需要这种级别的生物信息学支持，因此这一核心将由NINDS中心的这笔赠款和COLD共同支持(50：50)。

SUMMARY & RELEVANCE The Bioinformatics Core represents a new initiative for this renewal of the Center grant, taking the place of the Expression Profiling (Affyrrietrix) 'Core facility, which is now self-sustaining. The proposed Bioinformatics Core will facilitate the use of massively parallel sequencing (MPS) techniques, by providing neuroscientists with a dedicated bioinformatician. This Core will also serve as a repository of expertise for NINDS-funded and other UNC neuroscience faculty, particularly with regard to the design of MPS experiments, analysis of data, and use of existing MPS infrastructure at UNC-Chapel Hill. Since this level of bioinformatics support is also needed by neuroscientists in the Carolina Institute for Developmental Disabilities (ClOD), this Core will jointly be supported (50:50) by this NINDS Center grant and by ClOD.