FASEB SRC on Lipids and Lipid Regulated Kinases in Cancer

描述(由申请者提供)：本提案请求部分支持美国实验生物学学会联合会(FASE B)夏季研究会议(SRC)，主题为“癌症中的脂质和脂质调节的激酶”。本次会议将于2014年7月27日至8月1日在科罗拉多州蒸汽船温泉的蒸汽船大度假村举行，请为会议2014年会议提供支持。这次为期4天半的会议将吸引约100-120名国内外科学家参加，目的是讨论脂类调节信号转导通路、脂类介体和脂靶的最新突破。会议将由连续九届专题会议组成，每届会议由该领域的一名杰出专家主持。FASE B夏季研究会议在世界范围内被认为是一个杰出的机制，通过该机制，初级科学家，如博士生、博士后研究员和新独立的调查人员可以与来自学术界和行业的知名科学家互动并公开讨论他们的工作，这些科学家是各自领域的领导者。2014年的会议将由玛丽·里兰博士和彼得·帕克博士组织，将是FASEB SRC同类会议中的第四次，延续了2007、2009和2012年举行的前几次非常成功的会议。在癌症治疗的临床干预方面，脂质信号转导领域受到了极大的关注。事实上，每一条脂质信号通路都与癌症的发生、发展和/或扩散有直接和因果的联系，因此许多制药和生物技术公司都有积极的药物发现计划，正在评估许多脂质信号转导酶作为人类癌症治疗干预的新靶点。因此，脂质信号通路的翻译和临床意义将在每一次主题会议上占据中心舞台，在这些会议上，成熟的研究人员将讨论他们研究的临床和治疗分支。我们希望，作为这次会议的直接结果，新的想法和合作将 会议将被锻造，参加会议的新受训人员和年轻研究人员不仅将接触到许多令人兴奋的研究领域，而且将把会议作为一种工具，将其研究推向令人兴奋的新方向。

DESCRIPTION (provided by applicant): This proposal requests partial support for the Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference (SRC) on 'Lipids and Lipid Regulated Kinases in Cancer". Support is requested for the 2014 meeting of this conference to be held on July 27-August 1, 2014, at the Steamboat Grand Resort in Steamboat Springs, CO. This 4 1/2-day conference will attract about 100-120 participants national and international scientists with the goal of discussing the latest breakthroughs in lipid-regulated signal transduction cascades, lipid mediators, and lipid targets. The meeting will consist of nine consecutive thematic sessions, each chaired by a distinguished expert in that field. FASEB Summer Research Conference are known world-wide as an outstanding mechanism by which junior scientists such as PhD students, post- doctoral fellows and newly independent investigators can interact with and openly discuss their work with established scientists from academics and industry who are leaders in their respective fields. The 2014 conference will be organized by Dr. Mary Reyland and Dr. Peter Parker and will be the fourth FASEB SRC conference of its kind, building upon previous highly successful conferences held in 2007, 2009 and 2012. The field of lipid signaling has received enormous attention with respect to clinical intervention in cancer therapy. Virtually every lipid signaling pathway has been directly and causally linked to cancer initiation, progression and/or dissemination, and for that reason many pharmaceutical and biotechnology companies have active drug discovery programs that are evaluating many lipid signaling enzymes as novel targets for therapeutic intervention in human cancer. The translational and clinical implications of lipid signaling pathways will therefore take center stage in every thematic session where established investigators will be discussing the clinical and therapeutic ramifications of their research. Our hope is that as a direct result of this conference, new ideas and collaborations will be forged and that the new trainees and young investigators who attend will not only be exposed to many exciting areas of research, but will use the conference as a vehicle to catapult their research in exciting new directions.