Pediatric Infectious Diseases and Immunity Training Program

描述(由申请人提供)：我们建议在华盛顿大学(吴)/圣路易斯儿童医院儿科传染病科开展儿科传染病与免疫博士后培训计划(PIDI-TP)。长期目标是培训学术内科科学家开展儿科传染病研究，包括宿主对感染的反应。吴医学中心为内科科学家提供了一个出色的培训环境，拥有国家认可的医院和全国一流的生物医学研究设施。华盛顿大学的许多教职员工都是传染病和人类免疫学领域的主要研究人员。PIDI-TP还将利用吴氏基因组研究所，该研究所是世界上最先进的基因组测序中心之一，在人类微生物组计划中发挥了主导作用。PIDI-TP导师来自吴氏儿科、内科、病理学与免疫学和分子微生物学系，他们是非常成功的研究人员，拥有独立的研究计划和指导内科科学家的经验。PIDI-TP项目主任将由儿科学教授兼儿科传染病科主任格雷戈里·斯托奇担任。联合项目主任将是病理学和免疫学副教授萨德·斯塔彭贝克。一个由三名资深吴教员和一名杰出的外部成员组成的咨询委员会将向PD和协理PD提供建议。执行委员会将监督实习生的招募和挑选，监督实习生的表现和职业发展，并评估计划的运作和结果。受训人员还将向奖学金监督委员会报告，这些委员会的调查结果将由PD、共同PD和执行委员会审查。要求每年支持两名受训人员，他们将从传染病、风湿病、新生儿、过敏/肺部/免疫学、肾病和重症护理的儿科奖学金计划中招募，并从圣路易斯儿童医院的住院医生，特别是拥有医学和博士学位的住院医生那里招募。这批申请者足以填补所要求的职位。学员将被分配到以下三个课程之一：“病原体”、“宿主”和“基因组学/微生物组/病原体发现”。每名PIDI-TP学员将在项目导师的监督下获得一次主要的研究经验。核心课程将提供研究设计、生物统计学、研究伦理、人类科目、动物科目、科学写作、补助金准备和基因组学方面的培训，并将辅之以针对受训者所选轨道的个性化课程。受训人员还将在职业规划和备考专科委员会考试方面获得协助。职业发展将由研究导师、PD和共同PD、执行委员会和SOC进行监测。计划评估将包括短期和长期指标以及来自当前和过去受训人员的意见。将努力增加学员和导师的多样性。

DESCRIPTION (provided by applicant): We propose a post-doctoral training program in pediatric infectious diseases and immunity (PIDI-TP) based in the Pediatric Infectious Diseases Division of Washington University (WU)/St. Louis Children's Hospital. The long-term objective is to train academic physician-scientists to carry out research in pediatric infectious diseases including host response to infections. WU Medical Center offers an outstanding training environment for physician-scientists with nationally recognized hospitals conjoined with one of the nation's premier biomedical research facilities. Many Washington University faculty members are leading investigators in infectious diseases and human immunology. PIDI-TP will also take advantage of the WU Genome Institute, one of the world's most advanced genome sequencing centers that has played a leading role in the Human Microbiome Project. PIDI-TP mentors, drawn from the WU Departments of Pediatrics, Medicine, Pathology & Immunology, and Molecular Microbiology are highly successful investigators with independent research programs and experience in mentoring physician-scientists. The PIDI-TP Program Director will be Gregory Storch, Professor of Pediatrics and Director of the Division of Pediatric Infectious Diseases. The co-Program Director will be Thad Stappenbeck, Associate Professor of Pathology & Immunology. An Advisory Committee consisting of three senior WU faculty members and one distinguished outside member will advise the PD and co-PD. An Executive Committee will oversee recruitment and selection of trainees, monitor the performance and career development of trainees, and evaluate program operations and outcomes. Trainees will also report to Scholarship Oversight Committees, whose findings will be reviewed by the PD, co-PD, and Executive Committee. Support is requested for two trainees per year, to be recruited from pediatric fellowship programs in Infectious Diseases, Rheumatology, Neonatology, Allergy/Pulmonary/Immunology, Nephrology, and Critical Care, and from residents at St. Louis Children's Hospital, especially those with MD and PhD degrees. This pool of applicants is sufficient to fill the positions requested. Trainees will be assigned to one of three tracks: "Pathogens", "Host", and "Genomics/Microbiome/Pathogen Discovery". Each PIDI-TP trainee will have a major research experience under the supervision of a program mentor. A Core Curriculum will provide training in study design, biostatistics, research ethics, human subjects, animal subjects, scientific writing, preparation of grants, and genomics, and will be supplemented by an individualized curriculum, specific for the trainee's chosen track. Trainees will also receive assistance in career planning and in preparation for subspecialty Board examinations. Career development will be monitored by research mentors, the PD and co-PD, the Executive Committee and the SOCs. Program evaluation will include short-term and long-term metrics plus input from current and past trainees. Efforts will be made to enhance diversity of trainees and mentors.