Pittsburgh Older Americans Independence Center

描述(由申请者提供)：在美国老年人中培养最佳的平衡和灵活性，并减少伤害性跌倒。我们这个五年续展奖项的目标是：1.促进多学科的基础、转换和临床研究，探讨与年龄相关的平衡和行动能力改变的原因、后果和治疗；2.在充满活力的智力和协作环境中培训来自多个学科的年轻研究人员；3)作为资源和部分：其他OAIC、研究人员、机构和公众的中坚力量。我们的主题已经从关注平衡和衰老演变为更好地融合了当代关于平衡和移动性之间的接口的观点，特别是在负重活动中控制运动的作用。OAIC有三个资源核心(RCI-临床和人口研究核心，RC2-技术核心和RC3-数据管理和分析核心)，一个RCDC，一个PESC和一个LAC。我们提出了四项试验性研究和三个发展项目，反映了我们计划的范围和合作精神。该计划整合了50多个外部资助的项目，资助了3名胡椒学者，并为另外20多名通过其他机构和个人职业奖励来源资助的年轻调查人员提供支持和培训

DESCRIPTION (provided by applicant): Foster optimal balance and mobility and reduce injurious falls among older Americans. Our goals for this five year renewal award are to i. Promote multidisciplinary basic, translational and clinical inquiry into the causes, consequences and treatment of age related changes in balance and mobility, 2. Train young investigators from multiple disciplines within a vibrant intellectual and collaborative environment and 3) Serve as a resource and part:ner to other OAICs, investigators, institutions and the public. Our theme has evolved from a focus on balance and aging to one that better incorporates contemporary perspectives about the interface between balance and mobility, especially the role of control of motion during weight bearing activity. The OAIC has three Resource Cores (RCi- Clinical and Population Research Core, RC2- Tech Core and RC3- Data Management and Analysis Core) an RCDC, a PESC and an LAC. We propose four pilot studies and three developmental projects that reflect the scope and collaborative spirit of our program. The program integrates over 50 externally funded projects, funds three Pepper Scholars and provides support and training to over 20 additional young investigators who are funded through other sources of institutional and individual career awards