Pediatric Neurology Physician Scientist Program.

描述（由申请人提供）：在发育神经科学，成像，遗传学和分子治疗学的快速发展，使儿童神经病学成为生物医学的焦点。作为一名儿童神经病学住院医师项目主任，我对每一批新的住院医师申请者越来越多的资格感到惊讶，他们被我们专业面临的基本问题所吸引。在马萨诸塞州总医院，我们拥有一批对研究感兴趣的优秀住院医师，大量的基础科学进展等待转化为医学现实，一个非常丰富的研究环境，以及一个PI，指导委员会和一群精心挑选的导师，他们将共同指导这些学员发展成为成功的医生科学家。我们已经召集了一群由NIH资助的有成就的导师，他们的专业知识集中在儿童的大脑发育和神经系统疾病方面。这些都是经验丰富的研究人员，具有良好的培训医生科学家的记录。K12参与者不仅可以完全访问导师的实验室，还可以通过旨在加速马萨诸塞州总医院，哈佛医学院，哈佛公共卫生学院和马萨诸塞州理工学院神经科学研究的合作计划获得许多资源。精心设计的课程作业，书面评估以及与PI和儿童神经学共同导师的会议的精心结构的课程，以确保所有学者参与者顺利获得独立的研究资金。

DESCRIPTION (provided by applicant): Rapid advances in developmental neuroscience, imaging, genetics, and molecular therapeutics have thrust Child Neurology into the biomedical limelight. As a child neurology residency program director I am amazed at the increasingly spectacular qualifications of each new wave of resident applicants who are drawn to the fundamental problems facing our specialty. At Massachusetts General Hospital we are poised with a talented pool of residents interested in research, an abundance of basic science advances waiting to be translated to medical realities, an exceptionally rich research environment, and a PI, steering committee, and group of carefully selected mentors who together will guide the development of these trainees into successful physician scientists. We have assembled a group of accomplished NIH-funded mentors whose expertise is focused on brain development and neurological diseases of childhood. These are experienced investigators with a strong track record of training physician scientists. The K12 participants will have full access not only to their mentor's lab but also the many resources available through collaborative programs designed to accelerate neuroscience research at Massachusetts General Hospital, Harvard Medical School, Harvard School of Public Health, and the Massachusetts Institute of Technology. A carefully structured curriculum of coursework, written evaluations, and meetings with the PI and child neurology co-mentors has been carefully designed to ascertain that all scholar participants advance smoothly to independent research funding.