University of Massachusetts Center for Clinical and Translational Science

联系PD/PI：Luzuriaga，凯瑟琳 项目总结/摘要 马萨诸塞州大学（UMass）临床和转化科学中心（UMCCTS） 组织的愿景是改变临床和转化研究（CTR）和整个教育 五个马萨诸塞大学校园和我们的临床合作伙伴，马萨诸塞大学纪念医疗保健（UMMHC）。具体目标是 利用我们的科学优势和独特资源：1）加速发现的转化 转化为切实可行的、具有成本效益的解决方案，改善人类健康; 2）培训下一代 CTR的领导者在过去的五年里，UMCTS培养了一种跨学科的文化， 合作;提供核心、服务和试点项目;开发创新的教育和培训 程序.我们利用我们杰出的基础科学研究创造了一个生态系统， 加速了早期阶段的翻译，并促进了国家认可的计划的发展， 社区参与、健康差距、结果和全球健康。公私伙伴关系 将马萨诸塞大学校园定位为马萨诸塞州（MA）创新经济的中心。我们将继续 建立UMCCTS全州，国家和国际合作和影响：1。建设和 支持具有知识和专业知识的创新和协作翻译队伍 来提高点击率使用一种积极的方法来解决现实世界的问题， 教育，体验式培训和综合指导，以促进团队科学，我们将扩大CTR 通过修订课程、新的博士和博士后培训提供教育和培训机会 计划（链接TL 1奖），增强的KL 2学者计划，增加培训机会和职业生涯 支持我们的整个CTR劳动力; 2。让利益攸关方参与建立有利的系统和跨部门的 学科团队，提供科学的专业知识，资金，过程和工具，有利于 有效CTR。我们将继续扩大公私伙伴关系，将UMCTS建设成为一个 作为国家CTSA网络的贡献伙伴，我们将特别努力建设能力， 用于临床开发的先进产品。我们还将与CTSA网络合作，测试新的 改进临床试验的设计、完成和报告的方法， 人口、社区和全球健康; 3.将转化科学整合到多个阶段， 不同学科，在弱势群体中，在整个生命周期。我们将利用 在差异，LGBT，儿科和老年医学研究的具体专业知识，沿着在社区的成功 参与，以最大限度地提高我们在地方，国家和全球健康改善工作的影响 程度. 4.测试新方法，以制定和评估政策、流程和 支持CTR创新、质量、安全和效率的平台。 项目摘要/摘要第158页 联系PD/PI：Luzuriaga，凯瑟琳

Contact PD/PI: Luzuriaga, Katherine PROJECT SUMMARY/ABSTRACT The University of Massachusetts (UMass) Center for Clinical and Translational Science (UMCCTS) was organized with the vision of transforming clinical and translational research (CTR) and education across the five UMass campuses and our clinical partner, UMass Memorial Health Care (UMMHC). Specific goals were to leverage our scientific strengths and unique resources: 1) to accelerate the translation of discoveries into practical, cost effective solutions that improve human health; and 2) to train the next generation of leaders in CTR. Over the past five years, the UMCCTS has fostered a culture of trans-disciplinary collaboration; provided cores, services, and pilot programs; and developed innovative educational and training programs. We have capitalized on our outstanding basic science research to create an ecosystem that accelerates early phase translation and have facilitated the development of nationally recognized programs in community engagement, health disparities, outcomes, and Global Health. Public-private partnerships have positioned UMass campuses as hubs in the Massachusetts (MA) innovation economy. We will continue to build the UMCCTS for statewide, national, and international collaboration and impact by: 1. Building and supporting an innovative and collaborative translational workforce with the knowledge and expertise to advance high impact CTR. Using an active approach to solving real-world problems that combines didactic education, experiential training, and integrated mentorship to facilitate team science, we will expand CTR educational and training opportunities through revamped curricula, a new PhD and postdoctoral training program (linked TL1 award), an enhanced KL2 Scholars program, increased training opportunities and career support for our entire CTR workforce; 2. Engaging stakeholders to build enabling systems and trans- disciplinary teams that provide the scientific expertise, funding, processes, and tools conducive to effective CTR. We will continue to expand public-private partnerships that build out the UMCCTS as a contributing partner in the national CTSA network; we will particularly work to build capacity to identify and advance products for clinical development. We will also collaborate with the CTSA network on testing new approaches to improving the design, completion, and reporting of clinical trials that result in improved population, community, and global health; 3. Integrating translational science across its multiple phases, diverse disciplines, within disadvantaged populations, and across the lifespan. We will capitalize on specific expertise in disparities, LGBT, pediatric, and geriatric research along with successes in community engagement to maximize the impact of our work on health improvement at the local, national, and global levels. 4. Testing new approaches to develop and evaluate the impact of policies, processes, and platforms that support innovation, quality, safety, and efficiency in CTR. Project Summary/Abstract Page 158 Contact PD/PI: Luzuriaga, Katherine