Investigation into host susceptibility and immune responses in young children with acute wheezing due to human rhinovirus group C infection

我们最近有了一个令人惊讶的发现，一种新的病毒群，人类鼻病毒C组(HRV-C)，导致了儿童急性哮喘的大部分。我们还发现，在年幼儿童的急性喘息发作中，有一半是由它引起的，而且它是唯一与过敏有关的呼吸道病毒。因此，HRV-C可能是变态反应与哮喘关系的关键。计划中的项目将专注于患有HRV-C喘息症的幼儿是否存在免疫系统相关缺陷。

We recently made the surprising discovery that a new viral group, human rhinovirus group C (HRV-C), causes the majority of acute asthma in children. We also found that it causes half of the acute wheezing attacks in younger children, and is the only respiratory virus associated with allergy. So, HRV-C may be the key to the relationship between allergy and asthma. The planned project will focus on whether young children who wheeze with HRV-C have related defects in their immune system.