Investigation of a new hypothesis that increased TGF? activity in developing fetal organs predisposes a women to polycystic ovary syndrome and associated metabolic disorders

你有没有想过为什么有些人会变胖，而另一些人则不会，无论他们吃多少？答案可能在于他们出生前发生了什么。这个项目调查了一个新的假说，这个假说是从多囊卵巢综合征的发现中发展出来的。患有这种综合症的女性超重和糖尿病的风险更高。如果这些假设被证明是正确的，那么从长远来看，降低这些代谢紊乱的发生率是可能的。

Have you ever wondered why some people get fat and other do not, no matter how much they eat? The answer could lie in what happened before they were born. This project investigates a new hypothesis that was developed from discoveries on polycystic ovary syndrome. Women with this syndrome are at increased risk of becoming overweight and diabetic. If the hypotheses prove correct it might be possible to reduce the incidence of these metabolic disorders in the longer term.