Developing and Improving Institutional Animal Resources (G20)

 描述（由申请人提供）：麻省理工学院的动物资源计划代表了一个重要的资源，是该研究所的各种生物医学研究任务的核心。本提案旨在寻求资金，以符合现行NIH和AAALAC标准的方式更换68号楼动物设施中的老化笼清洗器和高压灭菌器。68号楼是麻省理工学院集中式动物资源计划的重要组成部分，该计划包括每天容纳98，000只动物的185，000 gsf空间。本提案中记录了以下具体目标。具体目标1购买并安装两台更好的SW 6300 PT型笼式和机架式清洗机，两台C550型笼式和瓶式清洗机，一台更好的T224型隧道式清洗机，带垫料分配器，以取代现有的使用20年的笼式清洗机。具体目标2为68 North和68 South购买并安装两台高压灭菌器，为68 South的BL 2设施购买并安装一台SR-24 D-ADVPRO型高压灭菌器，以替换现有的20年旧设备。具体的改进直接关系到长期目标， 麻省理工学院的动物资源计划，这是为了提供最好的环境，由美国国立卫生研究院和其他来源的支持，科学探究，同时保持AAALAC认证，并确保人道关怀和使用实验室动物的最高标准。

 DESCRIPTION (provided by applicant): The Animal Resource Program at MIT represents a vital resource that is central to the various biomedical research missions of the Institute. This proposal seeks funds to replace aged cage washers and autoclaves in the Building 68 animal facility in a manner consistent with current NIH and AAALAC standards. Building 68 is a critical component of the centralized MIT Animal Resource Program that encompasses 185,000 gsf of space housing 98,000 animals on a daily basis. The following specific aims are documented in this proposal. Specific Aim 1 Purchase and install two Better Built Model SW6300PT cage and rack washers, two C550 cage and bottle washers and one Better Built Model T224 tunnel washer with a bedding dispenser unit to replace existing 20 year old cage washers. Specific Aim 2 Purchase and install two consolidated autoclaves for 68 North and for 68 South and a Consolidated Model SR-24D-ADVPRO autoclave for the BL2 facility in 68 South to replace existing 20 year old units. The specific improvements are directly related to the long term goal of MIT's Animal Resource Program, which is to provide the best possible environment for scientific inquiry supported by NIH and other sources, concurrently maintain AAALAC accreditation, and ensure the highest standards of humane care and use of laboratory animals.