Maintenance and Improvement of NINDS Infrastructure

美国国立卫生研究院NINDS设施规划/设备 35号楼，GF352-4 2015财年，以下实验室和研究支持区域进行了翻新： 1.为电路动力学和连接部主管Kevin Briggman博士进行实验室翻新。地点，NIH校区，35号楼。 2.波特神经科学研究中心二期混合研究所实验室大楼的搬迁和激活活动，NINDS是牵头研究所。地点，NIH贝塞斯达校区，35号楼。 3.对位于波特神经科学研究中心的冷藏农场房间进行翻新，该中心支持多个IC。地点，NIH贝塞斯达校区，35号楼。 4.对B翼中支持多个PI的Autoclaves进行翻新。地点，NIH贝塞斯达校区，49号楼。 5.完成树枝晶形态发生与可塑性科科长权远博士的实验室改造和装修工作。地点，NIH贝塞斯达校区，35号楼。 6.为分子生理学和生物物理科科长Kenton Swartz博士进行实验室翻新和装修。地点，NIH贝塞斯达校区，35号楼。 7.F翼项目混合研究所实验室翼的搬迁和激活活动。实验室建设包括两名PI的实验室和办公室的工作，这两名PI是FACS设施主任Dragan Maric博士和病毒免疫学和生命内成像科主任Dorian McGvern博士，以及一名新招聘的NINDS PI。地点，NIH贝塞斯达校区，10号楼。 8.完成计算结构生物学组主任Lucy Forrest博士的实验室翻新和装修工作。地点，NIH贝塞斯达校区，35号楼。 9.为突触和神经电路部主任魏路博士进行实验室翻新和装修。地点，NIH贝塞斯达校区，35号楼。 10.为克雷格·布莱克斯通博士进行实验室翻新和装修，细胞生物科科长。地点，NIH贝塞斯达校区，35号楼。 11.为分子神经药理科科长David Sibley博士进行实验室翻新和装修。地点，NIH贝塞斯达校区，35号楼。 12.改造PNRC共享动物设施的氯气再加压动物饮用系统。地点，NIH贝塞斯达校区，35号楼。 13.整修采购和行政办公用房。地点，NIH贝塞斯达校区，35号楼。 14.为遗传性肌肉疾病股股长Ami Mankodi博士进行实验室翻新。地点，NIH贝塞斯达校区，35号楼。 15.对神经免疫病科科长Bibiana Bielekova博士的办公室进行翻修。地点，NIH贝塞斯达校区，10号楼。 16.完成NCCAM Alex Chesler博士的实验室翻新，作为合作和共享空间安排的一部分。地点，NIH贝塞斯达校区，35号楼。 17.进行翻修，为中风科科长约翰·哈伦贝克博士增加两个办公室。地点，NIH贝塞斯达校区，10号楼。 18.进行翻新，安装17T磁共振磁铁以支持NINDS壁内PI。地点，NIH贝塞斯达校区，35号楼。 19.启动支持NIH内部PI的11.7T磁共振磁体设施的翻新计划。地点，NIH贝塞斯达校区，10号楼。 20.翻新实验室空间，为神经治疗发展股首席约瑟夫·施泰纳博士配备质谱仪。地点，NIH贝塞斯达校区，10号楼。 21.对NINDS技术转让办公室主任Laurie Arrants的办公套件进行翻新。地点，NIH贝塞斯达校区，31号楼。 购买了以下主要共享设备，以支持大量PI： 1.蔡司LSM 880共聚焦显微镜，用于光成像设备、突触功能部分以及突触和神经电路单元。 2.Waters Breeze 2分子生理学和生物物理学部分的高效液相色谱系统 3.Q Exactive HF标准质谱仪，用于临床蛋白质组学单位 4.徕卡TCS SP8病毒免疫学和活体成像质谱仪 5.用于多肽测序设备的LC-MS测序系统 6.用于临床神经外科的XFe96细胞外流量分析仪 7.为共享的NIMH/NINDS功能磁共振设备升级3T和4T磁共振扫描仪 8.临床中心的PET CT升级

NATIONAL INSTITUTES OF HEALTH NINDS Facilities Planning / Equipment Bldg 35, GF352-4 The following laboratories and research support areas underwent renovations during FY 2015: 1. Perform the lab renovation for Dr Kevin Briggman, Chief, Circuit Dynamics and Connectivity unit. Location, NIH Campus, Bldg 35. 2. Relocation and activation activities for the Porter Neuroscience Research Center Phase 2, Mixed institute laboratory building, with NINDS as the lead institute. Location, NIH Bethesda Campus, Bldg 35. 3. Perform a renovation to the freezer farm room located in the Porter Neuroscience Research Center that supports multiple ICs. Location, NIH Bethesda Campus, Bldg 35. 4. Perform a renovation to the Autoclaves in B-Wing that supports multiple PIs. Location, NIH Bethesda Campus, Bldg 49. 5. Complete the lab renovation and fit-out for Dr Quan Yuan, Chief, Dendrite Morphogenesis and Plasticity Unit. Location, NIH Bethesda Campus, Bldg 35. 6. Perform a lab renovation and fit-out for Dr Kenton Swartz, Chief, Molecular Physiology & Biophysics Section. Location, NIH Bethesda Campus, Bldg 35. 7. Relocation and activation activities for the F-Wing project, Mixed institute laboratory wing. Laboratory construction includes work for laboratories and offices for two PIs, Dr Dragan Maric Chief, FACS Facility and Dr Dorian McGavern, Chief, Viral Immunology and Intravital Imaging Section and one new NINDS PI recruit. Location, NIH Bethesda Campus, Bldg 10. 8. Complete the lab renovation and fit-out for Dr Lucy Forrest, Chief, Computational Structural Biology Unit. Location, NIH Bethesda Campus, Bldg 35. 9. Perform the lab renovation and fit-out for Dr Wei Lu, Chief, Synapse and Neural Ciruit Unit. Location, NIH Bethesda Campus, Bldg 35. 10. Perform the lab renovation and fit-out for Dr Craig Blackstone, Chief, Cell Biology Section. Location, NIH Bethesda Campus, Bldg 35. 11. Perform a lab renovation and fit-out for Dr David Sibley, Chief, Molecular Neuropharmacology Section. Location, NIH Bethesda Campus, Bldg 35. 12. Renovate the chlorine repressurization animal drinking system for the PNRC Shared Animal Facility. Location, NIH Bethesda Campus, Bldg 35. 13. Renovate the procurement and administrative offices. Location, NIH Bethesda Campus, Bldg 35. 14. Perform the lab renovation for Dr Ami Mankodi, Chief, Hereditary Muscle Diseases Unit. Location, NIH Bethesda Campus, Bldg 35. 15. Perform the renovation to the office for Dr Bibiana Bielekova, Chief, Neuroimmunological Diseases Unit. Location, NIH Bethesda Campus, Bldg 10. 16. Complete the lab renovation for Dr Alex Chesler, NCCAM, as part of a collaborative and shared space arrangement. Location, NIH Bethesda Campus, Bldg 35. 17. Perform a renovation to add two offices for Dr John Hallenbeck, Chief, Stroke Branch. Location, NIH Bethesda Campus, Bldg 10. 18. Perform a renovation to install a 17T MRI Magnet to support NINDS Intramural PIs. Location, NIH Bethesda Campus, Bldg 35. 19. Initiate a renovation plan for the 11.7T MRI Magnet facility that supports NIH Intramural PIs. Location, NIH Bethesda Campus, Bldg 10. 20. Perform a renovation to the laboratory space that houses Mass Spectrometers for Dr Joseph Steiner, Chief, Neurotherapeutic Development Unit. Location, NIH Bethesda Campus, Bldg 10. 21. Perform a renovation to the office suite for Laurie Arrants, Chief, NINDS Office for Tech Transfer. Location, NIH Bethesda Campus, Bldg 31. The following pieces of major shared equipment were purchased to support a large number of PIs: 1. Zeiss LSM 880 confocal microscope for the Light Imaging Facility, Synaptic Functions Section, and Synapse and Neural Circuit Unit. 2. Waters Breeze 2 HPLC System with Spectrophotometer for the Molecular Physiology & Biophysics Section 3. Q Exactive HF Standard Mass Spectrometer for the Clinical Proteomics Unit 4. Leica TCS SP8 Mass Spectrometer for the Viral Immunology & Intravital Imaging Unit 5. LC-MS system for sequencing for the Peptide Sequencing Facility 6. XFe96 Extracellular Flux Analyzer for the Clinical Neurosurgery Unit 7. 3T & 4T MRI scanner upgrades for the shared NIMH/NINDS fMRI Facility 8. PET CT upgrade for the Clinical Center