Houston Area Molecular Biophysics Program

描述（由申请人提供）：休斯顿地区分子生物物理学计划（HAMBP）是一个博士。在分子生物物理学的研究培训计划，涉及52名教师导师在六个教育/研究机构在休斯顿加尔维斯顿地区：贝勒医学院，莱斯大学，休斯顿大学，得克萨斯大学休斯顿医学院，得克萨斯大学医学博士。安德森癌症中心和得克萨斯大学医学分支。由于这类院校的教职员人数众多，而申请者亦各不相同，因此，我们建议把获资助的见习生人数增至12名。学生在教室和实验室进行严格的学习。他们在分子生物物理学的基础上获得了坚实的基础，接触到广泛的主题，并在世界一流的生物物理实验室进行尖端的论文研究。研究领域包括X射线晶体学、大分子电子显微镜、荧光、磁共振和其他类型的大分子光谱学、热力学、动力学、分子动力学、理论生物物理学、蛋白质折叠、核酸结构、分子识别等。所研究的生物结构的大小范围从肽和脂质介质到病毒、转录复合物和肌丝。受资助的学员包括4个代表性不足的少数民族，平均GRE成绩为83%瓦（Q），81%瓦（A），79%瓦（V）和71%瓦（Adv.），本科生平均GPA为3.55/4.0。每名受训人员的平均出版物数量为：过去受训人员6.4篇，所有受训人员4.6篇，包括许多引人注目的论文和期刊封面。校友在完成培训后获得了优秀的职位，并继续在高水平上进行研究。该方案由一个由所有伙伴机构代表组成的指导委员会管理，该委员会密切监测学员的进展情况，并就申请学生和导师的录取作出决定。HAMBP是合作机构的几个非常成功的合作培训和研究企业之一，这些合作机构共同代表了比美国任何一个单一机构更大的研究资源和学员库。

DESCRIPTION (provided by applicant): The Houston Area Molecular Biophysics Program (HAMBP) is a Ph.D. research training program in molecular biophysics involving 52 faculty mentors in six educational/research institutions in the Houston-Galveston area: Baylor College of Medicine, Rice University, University of Houston, University of Texas-Houston Medical School, University of Texas M.D. Anderson Cancer Center, and University of Texas Medical Branch. Because of the large number of faculty, and the large and diverse applicant pool represented by this group of institutions, we propose to increase our number of funded trainees to 12. Students pursue a rigorous course of study in the classroom and in the laboratory. They receive a strong foundation in the fundamentals of Molecular Biophysics, exposure to a broad range of topics, and pursue cutting-edge thesis research in world-class biophysics laboratories. Research areas include x-ray crystallography, macromolecular electron microscopy, fluorescence, magnetic resonance and other types of macromolecular spectroscopy, thermodynamics, kinetics, molecular dynamics, theoretical biophysics, protein folding, nucleic acid structure, molecular recognition, and others. Biological structures studied range in size from peptides and lipid mediators to viruses, transcription complexes, and muscle filaments. Supported trainees have included 4 underrepresented minorities, and have had average GRE scores of 83%tile (Q), 81%tile (A), 79%tile(V), and 71%tile (Adv.), with average undergraduate GPAs of 3.55/4.0. The average number of publications per trainee is 6.4 for past trainees, and 4.6 for all trainees, including many high-profile papers and journal covers. Alumni have secured excellent positions upon completion of training, and continue to perform research at a high level. The Program is administered by a Steering Committee of representatives from all partner institutions, which closely monitors the progress of trainees, and make decisions about admission of applicant students and mentors. HAMBP is one of several highly successful cooperative training and research ventures of the partner institutions, which together represent a larger pool of research resources and trainees than any single institution in the U.S.