Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program

描述（由申请人提供）：本提案是一份新的5年国家研究服务奖机构研究补助金的申请，用于支持约翰霍普金斯大学彭博公共卫生学院（BSPH）和约翰霍普金斯大学医学院（SOM）的艾滋病毒流行病学和预防科学培训计划，名为“约翰霍普金斯大学艾滋病毒流行病学和预防科学培训计划”。拟议的项目将由主任Chris Beyrer MD， MPH和副主任Shruti Mehta PhD， MPH领导。现招收博士预科生4名，博士后2名。该计划的使命是培养博士生和博士后成为艾滋病研究前沿的领导者，具有先进的能力和最先进的技能，在三个培训方向：艾滋病毒流行病学研究方法和转化科学，包括培训(1)人口和研究设计，包括识别，招募和留住与艾滋病毒研究和全球艾滋病毒流行病学队列研究相关的人口；(2)艾滋病毒人群的测量问题，包括监测、估计艾滋病毒流行率和发病率的创新方法，以及基于人群的疾病负担的新型测量方法；(3)推理技术，包括因果推理和数学建模的现代分析方法；(4)综合研究成果并将其转化为公共卫生实践，包括系统综述/元分析和实施科学。HIV临床流行病学和实验室科学，包括以下方面的培训：(1)与HIV相关的主要合并感染和合并症的流行病学，(2)基因、病毒学、免疫学和临床因素的频谱测量。艾滋病毒预防科学包括如何通过以下方面的培训来预防和减轻艾滋病毒的负担：(1)艾滋病毒获得和传播的行为科学方面；(2)艾滋病毒生物医学和行为预防试验的设计和分析，包括治疗预防研究（TasP）；(3)基于社区和人口层面的艾滋病毒预防和控制方法，超越个人行为改变。该项目的目标是通过约翰霍普金斯大学BSPH和SOM的观察、临床和预防科学家进行的异常创新、富有成效和协作性的艾滋病毒研究，创造一个丰富和互动的培训环境。

DESCRIPTION (provided by applicant): This proposal is an application for a new 5-year National Research Service Award Institutional Research Grant to support a training program in HIV Epidemiology and Prevention Sciences at the Johns Hopkins Bloomberg School of Public Health (BSPH) and the Johns Hopkins School of Medicine (SOM), entitled the "Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program." The proposed program would be led by Director Chris Beyrer MD, MPH, and Deputy Director Shruti Mehta PhD, MPH. We are requesting support for 4 pre- and 2 post-doctoral trainees. The program mission is to train pre-doctoral students and post- doctoral fellows to become leaders at the forefront of research in HIV/AIDS with advanced competencies and state-of-the-art skills in three training tracks: HIV Epidemiology Research Methods and Translational Sciences which includes training in (1) Populations and Study Designs, including identifying, recruiting, and retaining populations relevant for HIV research and global HIV epidemiological cohort studies; (2) Measurement issues in HIV populations, including innovative methods for surveillance, estimation of HIV prevalence and incidence, and novel population-based measures of disease burden; (3) Inference techniques, including modern analytical methods for causal inference and mathematical modeling; and (4) Synthesis and Translation of research findings to public health practice, including systematic reviews/meta-analyses and implementation science. HIV Clinical Epidemiology and Laboratory Sciences including training in (1) the epidemiology of major co-infections and co-morbidities associated with HIV, (2) Measurement of the spectrum of genetic, virologic, immunologic, and clinical factors. HIV Prevention Sciences including how to prevent and reduce the burden of HIV through training in (1) Behavioral Science aspects of HIV acquisition and transmission, (2) Design and Analysis of HIV biomedical and behavioral prevention trials, including treatment as prevention research (TasP), and (3) Community-based and Population-level approaches to HIV prevention and control beyond individual behavior change. The program goal is to create a rich and interactive trainee environment augmented by the exceptionally innovative, productive, and collaborative HIV research conducted by observational, clinical, and prevention scientists throughout Johns Hopkins BSPH and SOM.