Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in Uganda

 描述(由申请人提供)：虽然在艾滋病毒项目上投入了大量资源，但乌干达距离80%的普遍获得护理的目标仍然很远。虽然乌干达在过去30年里在艾滋病毒、结核病和疟疾方面开展了非常成功的研究合作，但这些工作的大部分都集中在临床研究上，这些发现并不总是转化为政策和实践的变化。目前，我们需要在实施科学(IMS)研究方面进行紧急和可比的投资，以加强对艾滋病毒流行病的反应。艾滋病毒/艾滋病方案提供的有效服务和艾滋病毒感染者的护理参与将使抗逆转录病毒药物达到最佳的公共卫生影响。Makerere大学健康科学学院(MakCHS)与加州大学旧金山分校(UCSF)在一系列科学研究方面进行了30多年的合作。我们计划利用这一基础并建立一支多学科团队，为IMS创建世界级的培训计划，专注于提供艾滋病毒/艾滋病服务和参与护理。根据我们计划拨款的结果，我们在马凯雷雷大学医学院提出了一个独特的多学科IMS研究培训计划。拟议方案的目标是：1)向乌干达学者提供实施科学领域的培训和指导；2)在Makerere大学医学院为乌干达和非洲其他机构建立IMS培训基地。这一培训计划的具体目标是：1)加强实施科学研究所需的科学领导和专门知识；2)通过将IMS研究纳入正在进行的能力建设计划，加强Makerere大学实施科学研究的可持续性；3)促进乌干达和美国学术研究机构和教师之间的合作；4)通过与政策制定者和艾滋病毒计划实施者的定期互动，加强受训者对与艾滋病毒预防、护理和治疗服务有关的循证决策的贡献；5)通过利用乌干达的额外可用资源(包括由国家卫生研究院、联合国艾滋病规划署和其他国际机构资助的项目)，优化培训；6)加强乌干达的研究能力，帮助受训者融入乌干达的机构并从事有独立资助的科学事业；7)在MakCHS建立IMS英才中心，作为非洲其他机构的培训场所。拟议的IMS培训计划将建立在MakCHS及其附属艾滋病毒计划(医学)、Makerere大学人文和社会科学学院(非医学)、加州大学旧金山分校和UCB的科学家之间的现有关系的基础上。在我们的五年计划中，我们预计将对乌干达学员进行如下培训：加州大学旧金山分校硕士学位项目候选人2名，马凯雷雷大学硕士学位项目候选人8名，长期非学位培训(包括博士后培训)候选人4名，单元证书课程候选人20名，短期非学位课程候选人700多名。

 DESCRIPTION (provided by applicant): Although significant resources have been invested in HIV programs, Uganda is still far from the universal access-to-care target of 80%. While Uganda has developed highly successful research collaborations in HIV, tuberculosis, and malaria over the last 30 years, most of this work has been focused on clinical research, and the findings have not always translated into policy and practice changes. At present, we need an urgent and comparable investment in implementation science (ImS) research to strengthen the response to the HIV epidemic. Effective service delivery by HIV/AIDS programs and engagement in care among HIV-infected individuals will allow antiretroviral medications to reach their optimal public health impact. Makerere University College of Health Sciences (MakCHS) has collaborated with the University of California, San Francisco (UCSF) for over three decades on a range of scientific studies. We plan to leverage this foundation and build a multi-disciplinary team to create a world-class training program for ImS focused on delivery of HIV/AIDS services and engagement in care. Building on the findings of our planning grant, we propose a unique multi-disciplinary ImS research training program at Makerere University School of Medicine. The goals of the proposed program are to: 1) provide training and mentoring in the field of implementation science to Ugandan scholars 2) establish an ImS training site at Makerere University School of Medicine for Uganda and other institutions in Africa. The specific objectives of this training program are to: 1) strengthen the scientific leadership and expertise needed for implementation science research; 2) strengthen the sustainability of implementation science research at Makerere University by integrating ImS research into on-going capacity building programs; 3) promote collaborations between academic research institutions and faculty in Uganda and those in the US; 4) Strengthen trainee contributions to evidence-based decision making related to HIV prevention, care and treatment services through regular interactions with policy makers and HIV program implementers; 5) optimize training through utilization of additional available resources in Uganda (including projects funded by the NIH, PEPFAR and other international agencies); 6) strengthen research capacity in Uganda by helping trainees to integrate into Ugandan institutions and pursue independently-supported scientific careers; 7) create a Centre of Excellence for ImS at MakCHS to serve as a training site for other institutions in Africa. The proposed ImS training program will build on existing relationships between scientists at MakCHS and its affiliated HIV programs (medical), the Makerere University College of Humanities and Social Sciences (non-medical), UCSF and UCB. During our five year program, we anticipate training Ugandan trainees as follows: 2 candidates in master's degree programs at UCSF, 8 candidates in master's degree programs at Makerere University, 4 candidates in long-term non-degree training (including post-doc training), 20 candidates in a modular certificate program and over 700 candidates in short-term non-degree programs.