Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in Uganda

项目摘要 尽管乌干达已经在艾滋病毒方案上投入了大量资源，但乌干达仍然远远没有达到 实现80%的普及保健目标。虽然乌干达已经开发了非常成功的研究 在过去的30年里，艾滋病、结核病和疟疾方面的合作，大部分工作都集中在 临床研究，研究结果并不总是转化为政策和实践的变化。目前我们 需要对实施科学（ImS）研究进行紧急和可比的投资，以加强 应对艾滋病疫情。通过艾滋病毒/艾滋病方案提供有效服务和参与护理 在艾滋病毒感染者中普及艾滋病毒/艾滋病知识将使抗逆转录病毒药物发挥最佳公共卫生作用。 Makerere大学健康科学学院（MakCHS）与加州大学合作， 旧金山弗朗西斯科（UCSF）超过三十年的一系列科学研究。我们计划利用这个 建立一个多学科的团队，为ImS创建一个世界一流的培训计划，重点是 提供艾滋病毒/艾滋病服务和参与护理。根据我们规划补助金的调查结果，我们 提出了一个独特的多学科的ImS研究培训计划在医学的Makerere大学学院。 拟议方案的目标是：1）提供执行领域的培训和指导 向乌干达学者传授科学2）在马凯雷雷大学医学院建立ImS培训基地， 乌干达和非洲其他机构。该培训方案的具体目标是：1）加强 实施科学研究所需的科学领导和专门知识; 2）加强可持续性 通过将ImS研究纳入持续能力， 建设项目; 3）促进乌干达学术研究机构和教师之间的合作 4）加强受训人员对艾滋病毒相关循证决策的贡献 通过与政策制定者和艾滋病毒方案的定期互动，提供预防、护理和治疗服务 5）通过利用乌干达现有额外资源（包括 由NIH、PEPFAR和其他国际机构资助的项目）; 6）加强研究能力， 通过帮助受训人员融入乌干达的机构， 7）在MakCHS创建ImS卓越中心，作为其他人的培训场所 非洲的机构。拟议中的ImS培训计划将建立在科学家之间现有的关系上 在MakCHS及其附属的艾滋病毒项目（医学），Makerere大学人文学院和 社会科学（非医学），UCSF和UCB。在我们的五年计划中，我们预计培训乌干达人， 培训人员如下：2名在加州大学旧金山分校硕士学位课程的候选人，8名在硕士学位的候选人 马凯雷雷大学的课程，4名长期非学位培训（包括博士后培训）的候选人， 20名候选人参加模块化证书课程，700多名候选人参加短期非学位课程。 1

Project Summary Although significant resources have been invested in HIV programs, Uganda is still far from the universal access-to-care target of 80%. While Uganda has developed highly successful research collaborations in HIV, tuberculosis, and malaria over the last 30 years, most of this work has been focused on clinical research, and the findings have not always translated into policy and practice changes. At present, we need an urgent and comparable investment in implementation science (ImS) research to strengthen the response to the HIV epidemic. Effective service delivery by HIV/AIDS programs and engagement in care among HIV-infected individuals will allow antiretroviral medications to reach their optimal public health impact. Makerere University College of Health Sciences (MakCHS) has collaborated with the University of California, San Francisco (UCSF) for over three decades on a range of scientific studies. We plan to leverage this foundation and build a multi-disciplinary team to create a world-class training program for ImS focused on delivery of HIV/AIDS services and engagement in care. Building on the findings of our planning grant, we propose a unique multi-disciplinary ImS research training program at Makerere University School of Medicine. The goals of the proposed program are to: 1) provide training and mentoring in the field of implementation science to Ugandan scholars 2) establish an ImS training site at Makerere University School of Medicine for Uganda and other institutions in Africa. The specific objectives of this training program are to: 1) strengthen the scientific leadership and expertise needed for implementation science research; 2) strengthen the sustainability of implementation science research at Makerere University by integrating ImS research into on-going capacity building programs; 3) promote collaborations between academic research institutions and faculty in Uganda and those in the US; 4) Strengthen trainee contributions to evidence-based decision making related to HIV prevention, care and treatment services through regular interactions with policy makers and HIV program implementers; 5) optimize training through utilization of additional available resources in Uganda (including projects funded by the NIH, PEPFAR and other international agencies); 6) strengthen research capacity in Uganda by helping trainees to integrate into Ugandan institutions and pursue independently-supported scientific careers; 7) create a Centre of Excellence for ImS at MakCHS to serve as a training site for other institutions in Africa. The proposed ImS training program will build on existing relationships between scientists at MakCHS and its affiliated HIV programs (medical), the Makerere University College of Humanities and Social Sciences (non-medical), UCSF and UCB. During our five year program, we anticipate training Ugandan trainees as follows: 2 candidates in master’s degree programs at UCSF, 8 candidates in master’s degree programs at Makerere University, 4 candidates in long-term non-degree training (including post-doc training), 20 candidates in a modular certificate program and over 700 candidates in short-term non-degree programs. 1