Research Training in Pediatric Endocrinology

 描述（由申请人提供）：本竞争性更新申请继续支持匹兹堡大学和匹兹堡儿童医院（CHP）的儿科内分泌学和糖尿病博士后研究培训计划。随着熟练的医生调查人员的即将到来的国家短缺，这个研究培训计划的目标，目前在其第20个年头，是提供细胞，分子，生理，遗传，发育，生物化学，流行病学，临床和儿科内分泌疾病的翻译方面的尖端培训，并推出我们的毕业生到生产性学术研究的职业生涯。我们的奖学金培训计划的毕业生的86%是在全职学术职位或正在追求额外的培训。该计划的学员是根据先前的学术记录和对学术研究生涯的承诺而选择的，最近申请人的数量和质量有所增加。该计划需要两到三年的指导研究（基础科学，临床或翻译）超出奖学金培训的第一个临床年。培训学院由在糖尿病，肥胖，遗传学，发育生物学，生殖轴和核激素受体研究方面具有专业知识的动态资助的科学家组成。培训教师导师的选择是因为他们的研究的高素质和翻译的相关性，他们的优秀记录的培训医学博士。和博士科学家，他们的长期生产力，他们在确保校外资金的成功，以及他们在跨学科项目的兴趣。受训者在儿科内分泌学和糖尿病科专家临床教员的监督下获得临床经验。在研究期间，受训者由受训者选择的初级培训导师和学术监督委员会（SOC）监督，该委员会监督和评估受训者的科学进步并协助职业发展。所有受训人员都参加负责任的研究培训。定期的评估，教学会议和正式的课程工作为每个受训者的科学努力提供了严格的知识基础。该计划的成就，其临界智力质量，新部门负责人的激励以及CHP和匹兹堡大学的巨大资源使其成为培训儿科内分泌医生科学家的杰出计划，鼓励他们过渡到K奖，并培养他们作为独立的RO1资助的研究人员的成功。基于这些众多的优势，这个研究培训计划提供了一个杰出的机制，通过它当代医生调查人员将获得在转化研究的成功和富有成效的学术生涯的基本工具。

 DESCRIPTION (provided by applicant): This competitive renewal applies for continued support for the post-doctoral research training program in pediatric endocrinology and diabetes at the University of Pittsburgh and Children's Hospital of Pittsburgh of UPMC (CHP). With the impending national shortage of skilled physician-investigators, the goal of this research training program, currently in its 20th year, is to provide cutting-edge training in cellular, molecular, physiologic, genetic, developmental, biochemical, epidemiologic, clinical and translational aspects of pediatric endocrine disorders and launch our graduates into productive academic research careers. 86% of the graduates of our fellowship training program are in full-time academic positions or are pursuing additional training. Trainees to the program are selected based on prior academic records and commitment to an academic research career with recent increase in numbers and quality of the applicants. The program entails two to three years of mentored research (basic science, clinical, or translational) beyond the first clinical year of fellowship training. The training faculty consists of dynamic funded scientists with expertise in diabetes, obesity, genetics, developmental biology, reproductive axis and nuclear hormone receptors research. The training faculty mentors are selected because of the high caliber and translational relevance of their research, their outstanding records of training M.D. and Ph.D. scientists, their long-term productivity, their success in securing extramural funding, and their interest in interdisciplinary projects. Trainees gain clinical experience under the supervision of the expert clinical faculty members of the Division of Pediatric Endocrinology and Diabetes. During the research years, the trainees are supervised by a primary training mentor chosen by the trainee and a scholarly oversight committee (SOC) that oversees and evaluates the trainee's scientific progress and assist with career development. All trainees participate in responsible conduct of research training. Regular evaluations, didactic conferences, and formal course work provide a rigorous intellectual foundation for each trainee's scientific endeavors. The achievements of this program, its critical intellectual mass, invigoration by a new division chief and the tremendous resources at the CHP and the University of Pittsburgh make this an outstanding program to train pediatric endocrine physician-scientists, encourage their transition to K awards, and cultivate their success as independent RO1 funded investigators. Based on these numerous strengths, this research training program provides an outstanding mechanism through which contemporary physician- investigators will obtain the tools fundamental for successful and productive academic careers in translational research.