Training in PharmacoNeuroImmune Substance Abuse Research

7.项目总结/摘要 这是一个跨学科的药物滥用研究培训计划的续期申请，名为“培训， 药物神经免疫学（PNI）药物滥用研究”（T32 DA 007097 -34）。PNI培训 计划<z.umn.edu/pni>满足了一个公认的需要，即培训生物医学科学家， 博士后水平的跨学科和翻译领域，重点是药物的相互作用， 滥用与神经和免疫系统，并整合我们对这些生理的理解， 与他们的行为对应物的互动。培训计划的一个重要组成部分是考虑到 滥用药物作为艾滋病毒/艾滋病的辅助因素，特别是与神经艾滋病有关。该计划已培训了48名 在过去的15年里，有35名博士后（共83名）。这些人担任有影响力的职位， 学术界政府和工业界我们的39名小学教师导师是一群才华横溢的实验室 在这些学科交叉点工作的基础和临床科学家。我们资金雄厚的教师 有丰富的经验，作为导师，并致力于培养博士前学生和博士后 在这个跨学科的环境中。为了用我们现有的资源完成我们的训练使命，我们 申请资助10个博士后和5个博士后名额。成功培训的所有要素 方案已经到位，并正在有效运作：正式的课程，包括两个核心 神经免疫相互作用和神经精神药理学课程和两次物质讨论会 床旁虐待与艾滋病毒/艾滋病：发病机制，治疗和预防。额外的关键培训 活动包括每两个月举办一次系列研讨会、一次研究进展专题讨论会和一次年度务虚会。新 在这一应用中，扩大的PNI培训内容包括：a）增加13名新教师作为教师; B） 开发在线学习模块，供项目学员和参与的本科生使用， 为多样性学生提供的相关夏季研究计划; c）开发独特的研究严谨培训 （d）为博士后研究员提供培训经验，重点是非学术性的 岗位PNI培训计划进一步加强了明尼苏达大学的强有力的倡议， 突出翻译研究，（中心翻译研究）和成瘾的指定为一个 明尼苏达大学的成立证明了AHC的主要研究优先事项 成瘾神经科学中心MNCAN。强调将成瘾研究作为优先事项， NIDA长期以来为研究人员提供的研究资金提供了额外的证据， 为药物滥用研究的博士前和博士后研究员提供培训的环境。

7. Project Summary/Abstract This is a renewal application for an interdisciplinary Drug Abuse Research Training Program titled “Training in PharmacoNeuroimmunology (PNI) Substance Abuse Research” (T32 DA007097-34). The PNI Training Program <z.umn.edu/pni> meets a well-recognized need to train biomedical scientists at the pre- and postdoctoral levels in an interdisciplinary and translational field that focuses on the interactions of drugs of abuse with the nervous and immune systems, and integrates our understanding of these physiological interactions with their behavioral counterparts. A critical component of the training program considers the role of drugs of abuse as co-factors in HIV/AIDS, specifically relating to NeuroAIDS. The program has trained 48 predoctoral and 35 postdoctoral (83 total) in the past 15 years. These individuals hold influential positions in academia, government, and industry. Our 39 primary faculty preceptors are a talented group of laboratory based and clinical scientists working at these intersections of disciplines. Our well-funded faculty preceptors have extensive experience as mentors and are committed to training predoctoral students and postdoctoral fellows in this interdisciplinary setting. To fulfill our training mission with our available resources, we are requesting funding for 10 predoctoral and 5 postdoctoral slots. All of the elements of a successful training program are in place and are functioning efficiently and effectively: a formal curricula, including the two core courses in Neuro-immune Interactions and Neuropsychopharmacology and two colloquium in Substance Abuse at the Bedside and HIV/AIDS: Pathogenesis, Treatment, and Prevention. Additional critical training activities include a bimonthly seminar series, a research-in-progress symposium, and a yearly retreat. The new expanded PNI training components in this application include: a) adding 13 new faculty as preceptors; b) developing online learning modules for use by program trainees and undergraduate students participating in the linked summer research program for students of diversity; c) developing a unique research rigor training component; and d) developing a training experience for postdoctoral fellows focused on nonacademic positions. The PNI training program is further enhanced by the University of Minnesota strong initiative to highlight translational research, (Center for Translational Research) and the designation of Addiction as one major research priority by the AHC, University of Minnesota evidenced by the establishment of Minnesota Center for Addiction Neuroscience MNCAN. The emphasized commitment to addiction research as a priority, and the long standing history of research funding to investigators by NIDA provide additional evidence of a rich environment for the training of pre and postdoctoral research fellows in substance abuse research.