Northern New England Clinical and Translational Research Network

项目总结 新英格兰北部临床和翻译研究网络(NNE-CTR)的使命是 开发和维持临床和转化性研究基础设施，以支持改善农村和 为缅因州、新罕布夏州和佛蒙特州的居民提供社区健康。这个目标将是 通过两个牵头机构的调查人员的互补和协同合作来完成， 缅因州医疗中心(MaineHealth系统的成员)和 佛蒙特州大学( 与 佛蒙特州大学健康网络 )、一个参与机构、南缅因州大学和两个 合作组织、达特茅斯协同临床和翻译科学研究所以及 达特茅斯初级保健合作研究网络(达特茅斯合作研究网络)。 东北地区拥有最大的 65岁以上居民的百分比，而NNE-CTR将支持临床和翻译研究 在所有类型的工作中，我们的努力将重点放在新西兰北部农村人口普遍存在的健康问题上 英国，包括癌症、心血管疾病和药物滥用，以及 影响农村医疗保健服务的提供。我们提议的网络成员有很长的历史 协作，为提议的网络提供坚实的平台。为实现这些目标，NNE-CTR 提出四个具体目标：1)改善临床和转化性研究的基础设施和支持 缅因州、新罕布夏州和佛蒙特州；2)通过以下方式提高翻译和临床研究能力和疗效 在NNE-CTR之间建立协作和协同的跨学科研究伙伴关系 机构，在强有力的试点项目计划的帮助下；3)建立创新的培训、指导和 在NNE-CTR机构培养临床和转化型科学家的专业发展计划； 以及4)提供基础设施，以支持社区实践和以实践为基础的初级保健研究 网络，特别是在农村地区，让临床、社区、公共卫生和其他利益攸关方参与 开发和开展与纽约北部临床和人口健康需求相关的研究 英国。为实现这些目标，NNE-CTR将确定以下主要组成部分活动： 管理核心；试点项目计划；专业发展核心；临床研究设计 流行病学与生物统计学核心；农村卫生研究与服务核心；翻译研究 技术核心；以及跟踪和评价核心。总而言之，通过开发能力和 横跨临床和转化科学的广泛研究所需的资源，NNE- CTR将提供加强临床研究和医疗保健服务的平台，以支持独特的 新英格兰北部农村的需求。

PROJECT SUMMARY The mission of the Northern New England Clinical and Translational Research (NNE-CTR) Network is to develop and sustain a clinical and translational research infrastructure that supports improvement in rural and community health for inhabitants in the IDeA states of Maine, New Hampshire and Vermont. This goal will be accomplished through complementary and synergistic collaborations of investigators in two lead institutions, Maine Medical Center (a member of the MaineHealth System) and the University of Vermont ( with the University of Vermont Health Network ), one participating institution, the University of Southern Maine, and two collaborating organizations, the Dartmouth SYNERGY Clinical and Translational Science Institute and the Dartmouth Primary Care Cooperative Research Network (Dartmouth CO-OP). The Northeast has the largest percentage of residents over 65 years of age, and while NNE-CTR will support clinical and translational studies of all types, our efforts will emphasize health problems endemic in the rural populations of northern New England, including cancer, cardiovascular disease, and substance abuse, as well as the barriers that compromise rural health care delivery. The members of our proposed network have a long history of collaboration, providing a solid platform for the proposed network. To accomplish these goals, NNE-CTR proposes four specific aims: 1) improve the infrastructure and support for clinical and translational research in Maine, New Hampshire and Vermont; 2) increase translational and clinical research capacity and efficacy by establishing collaborative and synergistic transdisciplinary research partnerships among the NNE-CTR institutions, aided by a vigorous Pilot Projects program; 3) establish innovative training, mentoring and professional development programs to develop clinical and translational scientists at the NNE-CTR institutions; and 4) provide the infrastructure to support community practices and practice-based primary care research networks, particularly in rural areas, to engage clinical, community, public health and other stakeholders in the development and conduct of research relevant to the clinical and population health needs of northern New England. To achieve these aims, NNE-CTR will establish the following Key Component Activities: Administrative Core; Pilot Projects Program; Professional Development Core; Clinical Research Design, Epidemiology and Biostatistics Core; Rural Health Research and Delivery Core; Translational Research Technologies Core; and the Tracking and Evaluation Core. In summary, by developing the capabilities and resources required for research spanning the broad spectrum of clinical and translational science, the NNE- CTR will provide the platform for enhancing clinical research and health care delivery to support the unique needs of rural northern New England.