Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program

描述（由申请人提供）：本提案是一项新的5年期国家研究服务奖机构研究补助金申请，用于支持约翰霍普金斯彭博公共卫生学院（BSPH）和约翰霍普金斯医学院（SOM）的艾滋病毒流行病学和预防科学培训计划，名为“约翰霍普金斯艾滋病毒流行病学和预防科学培训计划”。“拟议的计划将由主任克里斯贝勒医学博士，公共卫生硕士，和副主任什鲁蒂梅塔博士，公共卫生硕士领导。我们正在申请4名博士前和2名博士后培训生的支持。该方案的使命是培养博士前学生和博士后研究员成为艾滋病毒/艾滋病研究前沿的领导者，在三个培训轨道上具有先进的能力和最先进的技能：HIV流行病学研究方法和转化科学，包括（1）人群和研究设计，包括识别，招募，（2）艾滋病毒感染人群的计量问题，包括监测的创新方法、艾滋病毒流行率和发病率的估计，以及基于人口的疾病负担新计量方法;（3）推理技术，包括因果推理和数学建模的现代分析方法;（4）将研究结果综合并转化为公共卫生实践，包括系统评价/荟萃分析和实施科学。HIV临床流行病学和实验室科学，包括（1）与HIV相关的主要合并感染和合并症的流行病学，（2）遗传，病毒学，免疫学和临床因素谱的测量。 艾滋病毒预防科学，包括如何预防和减少艾滋病毒的负担，通过培训（1）艾滋病毒感染和传播的行为科学方面，（2）艾滋病毒生物医学和行为预防试验的设计和分析，包括治疗预防研究（TasP），以及（3）以社区为基础的和人口水平的方法，以艾滋病毒预防和控制超越个人行为改变。该计划的目标是创造一个丰富的和互动的实习生环境，通过观察，临床和预防科学家在约翰霍普金斯BSPH和SOM进行的非常创新，富有成效和协作的艾滋病毒研究来增强。

DESCRIPTION (provided by applicant): This proposal is an application for a new 5-year National Research Service Award Institutional Research Grant to support a training program in HIV Epidemiology and Prevention Sciences at the Johns Hopkins Bloomberg School of Public Health (BSPH) and the Johns Hopkins School of Medicine (SOM), entitled the "Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program." The proposed program would be led by Director Chris Beyrer MD, MPH, and Deputy Director Shruti Mehta PhD, MPH. We are requesting support for 4 pre- and 2 post-doctoral trainees. The program mission is to train pre-doctoral students and post- doctoral fellows to become leaders at the forefront of research in HIV/AIDS with advanced competencies and state-of-the-art skills in three training tracks: HIV Epidemiology Research Methods and Translational Sciences which includes training in (1) Populations and Study Designs, including identifying, recruiting, and retaining populations relevant for HIV research and global HIV epidemiological cohort studies; (2) Measurement issues in HIV populations, including innovative methods for surveillance, estimation of HIV prevalence and incidence, and novel population-based measures of disease burden; (3) Inference techniques, including modern analytical methods for causal inference and mathematical modeling; and (4) Synthesis and Translation of research findings to public health practice, including systematic reviews/meta-analyses and implementation science. HIV Clinical Epidemiology and Laboratory Sciences including training in (1) the epidemiology of major co-infections and co-morbidities associated with HIV, (2) Measurement of the spectrum of genetic, virologic, immunologic, and clinical factors. HIV Prevention Sciences including how to prevent and reduce the burden of HIV through training in (1) Behavioral Science aspects of HIV acquisition and transmission, (2) Design and Analysis of HIV biomedical and behavioral prevention trials, including treatment as prevention research (TasP), and (3) Community-based and Population-level approaches to HIV prevention and control beyond individual behavior change. The program goal is to create a rich and interactive trainee environment augmented by the exceptionally innovative, productive, and collaborative HIV research conducted by observational, clinical, and prevention scientists throughout Johns Hopkins BSPH and SOM.