Molecular Pathology and Imaging Core

项目概要（分子病理学和成像核心） 分子病理学和成像核心（MPIC）是宾夕法尼亚大学的一个独特实体， 为分子生物学中心的研究人员提供了巨大的服务、资源、专业知识和效率。 消化和肝脏疾病研究（CMSDLD）。MPIC在加工和生产方面拥有特定的专业知识， 分析与CMSDLD相关的所有组织类型，包括专用显微镜，以及其他 CMSDLD研究者研究所必需的试剂和设备;没有类似的资源 专业知识存在于宾夕法尼亚大学校园或附近的机构。此外，通过提供具有成本效益的 在这种方法中，MPIC特别有利于试点和可行性获奖者，他们获得MPIC补贴 研究人员和初级研究人员/准成员，其中许多人还没有独立的资金。 MPIC成立于1995年，作为计划项目赠款的一部分，1997年扩大为CMSDLD服务 调查员，并自成立以来，一直得到大量利用，非常成功，作为一个模式， 宾夕法尼亚大学众多其他中心和项目的核心设施， 在全国MPIC是CMSDLD的关键组成部分，提供基本的日常服务 以及尖端技术的CMSDLD调查。目前包括1,000多平方米 MPIC位于BRBII/III的9楼，由一位经验丰富的董事和技术总监领导， 由训练有素的员工提供支持。此外，MPIC与其他核心和中心合作， CMSDLD研究者可用的资源和服务，自上次竞争性更新以来， MPIC继续整合新的服务和技术。此外，本发明还 MPIC促进新的和令人兴奋的合作和研究方向。总的来说，MPIC服务于 CMSDLD通过追求以下两个相互关联的具体目标：（1）提高效率， CMSDLD成员的生产力，提供专业的技术资源，服务和专业知识， 消化道、肝脏和胰腺的组织学、病理学和成像;以及（2）整合新的 通过以下方式促进消化、肝脏和胰腺疾病研究的研究和发现的技术： 调查和预测CMSDLD成员的需求。因此，MPIC提供卓越的 实用性、质量、价值、经验、服务和对CMSDLD的承诺。

PROJECT SUMMARY (MOLECULAR PATHOLOGY & IMAGING CORE) The Molecular Pathology and Imaging Core (MPIC) is a unique entity at the University of Pennsylvania and provides tremendous service, resources, expertise, and efficiency for investigators of the Center for Molecular Studies in Digestive and Liver Diseases (CMSDLD). The MPIC has specific expertise in processing and analyses of all tissue types relevant to the CMSDLD and includes specialized microscopes, as well as other reagents and equipment essential for the research of CMSDLD investigators; no resource with similar expertise exists on the Penn campus or in nearby institutions. In addition, by providing cost-effective approaches, the MPIC is particular beneficial to Pilot and Feasibility awardees, who receive subsidies for MPIC services, and junior investigators/Associate Members, many of whom do not yet have independent funding. Established in 1995 as part of a Program Project grant, the MPIC expanded in 1997 to serve CMSDLD investigators and, since its inception, has been heavily utilized and extremely successful, serving as a model core facility for numerous other Centers and Program Projects at the University of Pennsylvania and throughout the country. The MPIC is a key component of the CMSDLD, providing essential, routine services as well as cutting edge technologies to CMSDLD investigators. Currently comprising more than 1,000 square feet on the 9th floor of BRBII/III, the MPIC is lead by an experienced Director and Technical Director and supported by a highly-trained staff. Moreover, working with other Cores and Centers, the MPIC expands the resources and services available to CMSDLD investigators, and since the last competitive renewal of this application, the MPIC has continued to incorporate and integrate new services and technologies. Additionally, the MPIC promotes new and exciting collaborations and research directions. Overall, the MPIC serves the CMSDLD by pursuing the following two interrelated Specific Aims: (1) To enhance the efficiency and productivity of CMSDLD members by providing specialized technical resources, services, and expertise in histology, pathology, and imaging of the digestive tract, liver, and pancreas; and (2) To integrate new technologies that advance research and discovery for studies of digestive, liver, and pancreatic diseases by both surveying and anticipating the needs of CMSDLD members. As such, the MPIC provides exceptional utility, quality, value, experience, service, and commitment to the CMSDLD.