Yale Core Grant for Vision Research

项目摘要 耶鲁大学视力研究核心计划的总体目标是加强耶鲁大学的视力研究。 该计划有四个关键模块，将通过提供以下方面帮助VISION调查人员正在进行的研究项目 个人研究拨款不能轻易支持的设施和专业知识。这些模块还可用于 促进和促进耶鲁大学视觉研究人员之间的协作互动 校园里。核心拨款还将促进试点项目，以鼓励耶鲁大学的资深研究人员进入 视觉研究领域并制定新的视觉研究资助建议。 在本申请中提出了四个关键模块。制造核心模块将协助设计， 开发和建造专门用于视觉研究的设备和仪器。这项服务 模块将提供必要的资源，帮助耶鲁大学视觉研究的新手和初级研究员获得 他们的实验室以最快的速度投入运行。还提出了三个资源模块。A编程 核心模块将支持定制数据采集和分析软件的开发以及 通过科学服务将专门的电子设备集成到实验平台中 程序员。成像核心模块将提供对物理设施和智力资源的访问，以 最先进的静态和动态成像固定和活的视觉系统组织。最后，基因分型和 病毒生产核心模块将在现代生物学研究中发挥重要作用，重点是 通过提供广泛的分子生物学途径，进行基因分型和生产新的病毒载体 不属于个人视觉研究人员专业领域的设备、技术和技能， 或者超出了他们的能力范围。这四个模块组成了一个组合的VISION核心程序，为 耶鲁大学所有视觉研究人员的需求。

Project Summary The overall objective of the Yale Vision Research Core Program is to enhance vision research at Yale University. With four key modules, this Program will aid the ongoing research projects of vision investigators by providing facilities and expertise that cannot be readily supported by individual research grants. The modules also serve to promote and facilitate collaborative interactions between vision investigators throughout the Yale University campus. The Core grant will also facilitate pilot projects to encourage established investigators at Yale to enter the field of vision research and develop new vision research grant proposals. Four key modules are proposed in this application. A Fabrication core module will assist in the design, development and construction of devices and instrumentation that are specific to vision research. This service module will provide an essential resource in helping new and junior investigators in vision research at Yale get their labs up and running as quickly as possible. Three resource modules are also proposed. A Programming core module will support the development of custom data acquisition and analysis software and the integration of specialized electronic equipment into experimental platforms through the services of a scientific programmer. An Imaging core module will provide access to physical facilities and intellectual resources for state-of-the art static and dynamic imaging of fixed and living visual system tissue. Finally, a Genotyping and Virus Production core module will serve an essential role in modern biological research, with a focus on genotyping and the production of novel viral vectors, by providing broad access to molecular biological equipment, techniques and skills that are either outside the area of expertise for individual vision researchers, or beyond their capabilities to utilize. These four modules make up a combined vision core program that serves the needs of all vision researchers at Yale University.