Academic Pediatric Infectious Disease

摘要 我们的华盛顿大学（UW）儿科传染病（PID）培训计划的目标 (TP)是培养未来儿童传染病研究的领导者。我们的TP（1）新兵经验丰富 和致力于儿科医生;（2）培训他们在基础和新的分子，基因组学，蛋白质组学，生物信息学， 和流行病学方法，和（3）指导他们开发和领导一个独立的研究计划。 我们要求延长T32的支持，每年培训四名儿科医生进行研究。起初，每个人 在西雅图儿童医院（SCH）的支持下，参加12个月的临床培训（用于PID认证）。 随后，T32将支持培训学院（TF）为期2年的指导研究，TF是以下领域的领导者： 他们的研究领域，并擅长指导。鼓励学员和TF处理项目， 为理解和治疗儿科感染性疾病提供新颖和关键的见解，并产生 K、R或其他奖励的初步数据。此外，研究员还在研究所接受教学和实践教育。 管理人类和/或动物研究、资助和手稿准备的联邦法规，以及 在学术界取得成功的策略。我们的课程包括过渡到"K"系列NIH的结构化时间轴 如有需要，本署会提供支援，协助学员顺利过渡。 自1981年以来，我们的NIH T32支持的UW-PID-FP已经培训了94名研究员， 母婴健康研究领导者（图1）。在过去的15年里，34名研究员成功地 完成了我们的TP，1转移到不同的TP，和9目前的研究员。截至2017年5月，34个TP中 在过去15年的毕业生中，有18人（53%）获得了Ks。完成我们的TP的毕业生更多 与5年前相比（因此在该阶段，一个人将发展到NIH R级资助），11/26（42%） 收到Rs。生物医学研究仍然是过去15年中26/34（76%）毕业生的主要重点 年：17个领先的学术实验室（R，K或基金会资助的PI），2个是学术研究科学家，4个是领先的 政府机构内部的研究人员与内部基金，1是行业研究员，2是 大学生物学教授教授本科生和进行研究。其余8/34（24%） 包括：2名临床医生教育者在学术医院参与研究，6名临床医生 传染病专家。我们有9名现任研究员和1名新研究员于2017年7月进入;其中8名 提交了至少1份K和/或基金会赠款的个人申请; 4份获得了奖项，6份获得了 待处理的申请。在我们目前的研究员和最近的毕业生（N = 43）从过去15年，6（14%） 在健康科学领域代表性不足的少数民族。2017年，两名研究员将完成他们的第三年， 奖学金，两人将继续作为第四年的高级研究员/导师与我们的部门或他们的资金 等待K和/或其他补助金申请;另外2人将完成他们的第四年奖学金，一个加入 乔治城大学担任助理教授，另一位目前正在3所大学的录取通知书中做出决定。

ABSTRACT The objective of our University of Washington’s (UW) Pediatric Infectious Diseases (PID) Training Program (TP) is to train future leaders in research on infectious diseases of children. Our TP (1) recruits experienced and committed pediatricians; (2) trains them in basic and novel molecular, genomic, proteomic, bioinformatic, and epidemiologic methods, and (3) mentors them to develop and lead an independent research program. We request the renewal of T32 support to train four pediatricians in research annually. Initially, each fellow engages in 12 months of clinical training (for PID certification), supported by Seattle Children's Hospital (SCH). Subsequently, the T32 will support 2 years of mentored research by Training Faculty (TF) who are leaders in their areas of research and excel at mentorship. Trainees and TF are encouraged to tackle projects that will contribute novel and critical insights into understanding and treating pediatric infectious diseases and generate preliminary data for a K, R, or other award. In addition, fellows receive didactic and hands-on education in the federal regulations governing research with humans and/or animals, grant and manuscript preparation, and strategies to succeed in academia. Our curriculum includes a structured timeline to transition to “K”-series NIH awards, and if needed, our department extends support to assist trainees in this transition. Our NIH T32-supported UW-PID-FP has trained 94 fellows since 1981, with a consistent record of developing research leaders in Maternal-Child Health (Figure 1). During the past 15 years, 34 fellows have successfully completed our TP, 1 transferred to a different TP, and 9 are current fellows. As of May 2017, of the 34 TP graduates from the past 15 years, 18 (53%) have been awarded Ks. Of the graduates completing our TP more than 5 years ago (and therefore at the stage one would progress to NIH R-level funding), 11/26 (42%) have received Rs. Biomedical research continues to be a primary focus of 26/34 (76%) graduates from the last 15 years: 17 lead academic labs (PIs of R, K or foundation grants), 2 are academic research scientists, 4 are lead researchers within government institutions with intramural funds, 1 is an industry researcher, and 2 are university biology professors teaching undergraduates and performing research. The remaining 8/34 (24%) include: 2 clinician educators at academic hospitals where they participate in research, and 6 clinical specialists in infectious diseases. We have 9 current fellows and 1 new fellow entering in July 2017; 8 of these have submitted ≥1 individual applications for K and/or foundation grants; 4 received awards, and 6 have pending applications. Among our current fellows and recent graduates (N=43) from the past 15 years, 6 (14%) are under-represented-minorities (URM) in health sciences. In 2017, two fellows will complete their 3rd year of fellowship and both will continue as 4th-year Senior Fellows/Instructors with funding by our department or their pending K and/or other grant applications; 2 others will complete their 4th-year of fellowship, one joining Georgetown University as an Assistant Professor and the other currently deciding between 3 university offers.