Training Program in Neurobiology of Information Storage

项目总结 此应用程序寻求续订 信息存储神经生物学培训计划(NISTP)，这是 致力于 准备出众 博士前 面向学习科学研究密集型职业的学生 和记忆。该计划自2003年开始实施，重点是基本信息机制方面的培训 动物和人类的储存，是西北大学这一领域研究的中心组织者。使用 最近心理健康研究向维度的、基于系统的框架的转变 对通过该计划提供的这类培训的需求前所未有，该计划提供多个 了解学习和记忆的机制及其与心理健康的相关性的分析水平。 NISTP基于西北大学跨部门神经科学(NUIN)计划， 从一个由29名互动调查人员组成的多学科小组中脱颖而出，他们成功地参与了 分子/遗传、细胞/回路和系统/行为决定因素的合作研究 信息存储。NISTP导师在博士前培训方面有很好的记录，资金充足 研究计划，可以向一群优秀的发展中的人传授基础和临床观点 科学家。NISTP的培训部分将包括：1)关于最新研究的高级课程 信息存储神经生物学，由NISTP讲师授课；2)两个由学员主办的讲座系列，内容包括 信息存储领域的领先研究人员；3)为准备NRSA的学员提供模拟学习部分 申请；以及4)NISTP季度会议，包括a)“正在进行的研究”实习生讲座，b)“长凳到 床边“翻译讨论”，c)“计算建模和记忆”互动讨论，以及d) NISTP年度务虚会。NISTP还服务于对学生进行科学伦理教育并招收学生 从代表不足的群体到研究学习和记忆。将对该计划进行持续评估 使用定性机制，如受训人员的评估，以及量化措施，如 如跟踪前学员的研究效率、资金和职业发展轨迹。内置式转向装置 委员会和外部咨询委员会将进行额外的评估程序。 主要从已完成大部分必修课程并拥有 我们需要继续支持五个实习生职位， 将补充一个机构资助的“附属机构”位置。有了NISTP的附加值，我们 相信NISTP学员将从他们的研究生培训中脱颖而出，准备在 学习和记忆的基本生物学机制，并处于开发新的翻译 申请。 在他们的论文研究方面取得了重大进展。

PROJECT SUMMARY This application seeks to renew the Neurobiology of Information Storage Training Program (NISTP), which is devoted to preparing exceptional predoctoral students for research-intensive careers in the science of learning and memory. Active since 2003, the program is focused on training in fundamental mechanisms of information storage in animals and humans, acting as a central organizer for research in this area at Northwestern. With the recent shift in mental health research toward dimensional, systems-based frameworks there is unprecedented need for training of the kind offered through this program, which provides training at multiple levels of analyses for understanding mechanisms of learning and memory and their relevance to mental health. The NISTP is based in the Northwestern University Interdepartmental Neuroscience (NUIN) program, emerging from a multidisciplinary group of 29 interactive investigators who have successfully engaged in collaborative research on molecular/genetic, cellular/circuit, and systems/behavioral determinants of information storage. NISTP preceptors have strong track records in predoctoral training and well-funded research programs, and can impart both basic and clinical perspectives to a group of outstanding developing scientists. Training components of the NISTP will include: 1) an advanced course in the latest research in information storage neurobiology, taught by NISTP preceptors; 2) two trainee-hosted lecture series featuring leading investigators in the field of information storage; 3) mock study sections for trainees preparing NRSA applications; and 4) quarterly NISTP meetings including a) “research in progress” trainee talks, b) “bench to bedside” translational discussions, c) “computational modeling and memory” interactive discussions, and d) the annual NISTP retreat. NISTP also serves to educate students in the ethics of science and to recruit students from underrepresented groups to study learning and memory. Continuous evaluation of the program will be accomplished using qualitative mechanisms, such as evaluations by trainees, and quantitative measures, such as tracking the research productivity, funding, and career trajectories of former trainees. An internal Steering Committee and an External Advisory Committee will conduct additional assessment processes.Trainees are drawn primarily from a pool of NUIN students who have completed most of the required coursework and have We r equest continued support for five trainee slots, which will be supplemented with one institutionally funded “affiliate” slot . With the value added by the NISTP, we are confident that NISTP trainees will emerge from their graduate training poised to advance research in fundamental biological mechanisms of learning and memory and well positioned to develop novel translational applications. made significant progress in their thesis research.