NRSA Hepatology Training Grant

项目总结/摘要 肝病学博士后培养计划是肝病学综合研究的重要组成部分 在UCSF的项目。该计划的目的是为学员提供肝脏生物学的坚实背景， 疾病以及研究技能，以解决新的问题，并有助于新的知识， 肝病学该方案由内科和外科的12名教员组成; 总的来说，这些人在基础和临床肝病学方面提供了平衡的专业知识， 相互合作的记录。一个由6名项目教师组成的小组， 负责筛选申请人、审查培训课程和监测 活跃的学员。该计划的首要任务是培养被UCSF录取的医学科学家， 胃肠病学研究员。申请该计划的MD申请人必须有先前的研究成果记录 并致力于肝病学的独立研究事业。博士申请者主要来自 导师实验室;他们必须表现出类似的学术承诺和对翻译肝脏的方向 research.所有学员都将通过核心课程，涵盖肝脏生物学，肝脏相关研究 方法和一般学术技能。然后，他们在一个人的指导下接受专门的研究指导， 导师，选择范围从临床流行病学，健康结果和遗传学细胞生物学， 免疫学、代谢和纤维化/致癌作用。强烈推荐额外的重点课程 对于所有学员;对于那些追求临床研究，在硕士学位课程注册是强制性的。 重要的是，培训计划受益于众多的机构资源，包括杰出的 基础和临床科学的研究生课程以及研究支持单位，如肝脏中心 和临床与转化科学研究所项目教师是这些单位中每一个强大的数字， 从而引导学生利用这些资源，实现博士后价值最大化 体验.培训计划的最终目标是提供足够的团体和个人指导 使毕业生能够承担一个学院级的职位，并成功地竞争独立的研究 肝脏病学的资助。

Project Summary/Abstract The Postdoctoral Training Program in Hepatology is an integral part of the comprehensive hepatology research program at UCSF. The purpose of the Program is to provide trainees a solid background in liver biology and disease as well as the investigational skills to address new questions and contribute to new knowledge in hepatology. The Program is staffed by 12 faculty based within the Departments of Medicine and Surgery; collectively these individuals offer balanced expertise in basic and clinical hepatology and have a strong track record of working collaboratively with each other. A subgroup of 6 Program faculty comprise a Steering Committee charged with screening applicants, reviewing the training curriculum and monitoring the progress of active trainees. The top priority of the Program is to train physician-scientists who are admitted to UCSF as Gastroenterology fellows. MD applicants to the Program must have a prior record of research accomplishment and dedication to an independent investigative career in hepatology. PhD applicants are admitted largely from mentor laboratories; they must display similar academic promise and an orientation toward translational liver research. All trainees are placed through a core curriculum covering liver biology, liver-related research methods and general academic skills. They then undergo specialized research instruction under an individual mentor, with choices ranging from clinical epidemiology, health outcomes and genetics to cell biology, immunology, metabolism and fibrosis/carcinogenesis. Additional focused coursework is highly recommended for all trainees; for those pursuing clinical investigation, enrollment in a Master's Degree program is mandatory. Importantly, the Training Program benefits from numerous institutional resources including outstanding graduate programs in basic and clinical sciences as well as research support units such as the Liver Center and the Clinical and Translational Sciences Institute. Program faculty are strong figures in each of these units, and accordingly can guide trainees to utilize these resources to maximize the value of their postdoctoral experience. The ultimate goal of the Training Program is to provide sufficient group and individual mentorship to enable graduates to assume a faculty-level position and compete successfully for independent research funding in hepatology.