RNA Science and Technology in Health and Disease

1.项目摘要 RNA研究员计划的总体目标是严格培养研究生的职业生涯， 科技公司、科学传播组织、公共服务或学术界。我们 RNA研究员将规划和执行以RNA为中心的研究项目，并积极参与为期一年的业务 策划竞赛或写作活动，使他们能够成为合格的科学企业家或科学 沟通者这些独特的经验将帮助我们的学生把他们的科学为基础的培训， 制药、生物技术、创业、金融、公共政策、新闻和其他非传统 领域的我们独特的T32培训补助金旨在培养学生在学术界以外的职业生涯，但它将 让他们在传统的博士后环境中脱颖而出，如果他们这样选择。我们将培养学生， 利用RNA科学和技术的潜力，通过在化学，分子，纳米 科学和公共卫生学科，因为我们利用RNA的智力资本和资源， 研究所成员来自奥尔巴尼大学、纽约州立大学（纽约的州立大学）和纽约州立大学理工学院 院RNA研究员计划将为学生提供四个部门的学位课程，生物学， 科学，生物医学科学，化学和纳米生物科学，独特的研究和教育 经验，将提供专业和个人技能，以满足切割所需的挑战 尖端科技劳动力。博士研究项目将从基础生物学扩展到 从基因表达、健康和疾病中的RNA到生物学、化学、 生物物理学、计算、纳米科学、纳米工程和信息学。有六种RNA 代表导师教师兴趣的研究主题（i）RNA结构的计算分析;（ii） RNA序列和结构的实验分析;（iii）技术开发;以及三个生物医学领域 （一）基本细胞过程;（二）传染病;（三）发展和癌症。两个- 基于这些主题的学期旗舰RNA课程和数学或生物医学流畅性课程将 通过黑石创业计划， 分别在我们的商学院或著名的纽约州立作家研究所启动。作为证据 在机构的支持下，我们实施了一项由纽约州立大学赞助的RNA研究员计划，共有18名 三年级的学生。33个培训学院平均每年获得超过37.2万美元的直接资助 支持并专注于我们的RNA核心主题。UAlbany对学生多样性的坚定承诺， 29.9%的学生是少数民族。加上现有的积极招募 计划，我们目前的人口统计和我们在纽约路易斯斯托克斯少数民族联盟的参与 参与（LSAMP）使我们能够从代表性不足的背景中招募个人。 我们的T32培训补助金申请要求为20个学生名额提供资金，与超过100万美元的资金相匹配 从纽约州立大学的机构支持。 !

1. PROJECT SUMMARY The overall goal of the RNA Fellows program is to rigorously train graduate students for careers in science and technology companies, science communication organizations, public service or academia. Our RNA Fellows will plan and execute RNA centric research projects and actively participate in year-long business plan competitions or writing events, so that they can be qualified as science entrepreneurs or science communicators. These unique experiences will help our students bring their science based training to the pharmaceutical, biotechnology, business start-up, finance, public policy, journalism and other non-traditional fields. Our distinctive T32 training grant is designed to train students for careers outside academia, but it will allow them to excel in traditional post-doctoral environments if they so choose. We will prepare students to harness the potential of RNA science and technology by cross-training in chemical, molecular, nanoscale science, and public health disciplines, as we exploit the intellectual capital and the resources of the RNA Institute with members from University at Albany, SUNY (State University of New York) and SUNY Polytechnic Institute. The RNA Fellows program will give students in four departmental degree programs, Biological Sciences, Biomedical Sciences, Chemistry and Nanobiosciences, unique research and educational experiences that will provide the professional and personal skills to meet the challenges needed for a cutting edge science and technology workforce. Doctoral research projects will extend from the fundamental biology of RNA in gene-expression, health and disease to technology innovation at the interfaces of biology, chemistry, biophysics, computation, nanoscale science, nanoscale engineering and informatics. There are six RNA research themes representing mentor faculty interests (i) Computational Analysis of RNA Structure; (ii) Experimental Analysis of RNA Sequence and Structure; (iii) Technology Development; and three biomedical themes of (i) Basic Cellular Processes; (ii) Infectious Disease; and (iii) Development and Cancer. A two- semester flagship RNA course based on these themes and a course in mathematical or biomedical fluency will be combined with options to train in entrepreneurship or writing, via the Blackstone Entrepreneurship Launchpad at our School of Business or at the renowned NY State Writers Institute, respectively. As evidence of Institutional support, we have implemented a SUNY sponsored RNA Fellows program that has 18 total students from three yearly cohorts. The 33 training faculty have on average over $372K a year in direct grant support and focus on our RNA core themes. UAlbany has a strong commitment to student diversity with 29.9% of its students being under-represented minorities. Together with an existing aggressive recruitment plan, our current demographics and our participation in the New York Louis Stokes Alliance for Minority Participation (LSAMP) positons us to grow our recruitment of individuals from underrepresented backgrounds. Our T32 training grant application requests funding for 20 student slots, which is matched with over $1 million from SUNY in institutional support. !