MAPP Research Network Tissue Analysis and Technology Core

科罗拉多大学的TATC将继续提供专业知识和资源来支持MAPP-RN 在拟议的MAPP-第二阶段延展期内。TATC的成立是为了协助MAPP-RN 生物样品的收集、加工和分析。 TATC将与MAPP执行委员会和指导委员会、NIDDK、发现站点 团队和数据协调核心，以确保实现Mapp RN的目标。TATC将会见所有 NIH质量标准，并将与DCC和NIDDK中央存储库密切合作，以协调最终 在三年期末之前将所有残留生物检疫剂和辅助数据转移到中央储存库 延长期。 目前的资助期将于2019年6月结束。我们建议将资金延长三年，至2022年6月，以 完成以下任务： 特定目标1为MAPP RN提供生物库支持。TATC将继续充当 在延长的12个月跟踪窗口期间对卫生和植物检疫制度中收集的所有生物检疫样本进行中央存储库 研究和提供生物标本收集试剂盒、标本收集、处理、 集中处理和存档，以支持MAPP-II。 具体目标2：在标本相关数据收集和跟踪方面与DCC合作。我们 将继续就数据收集的最佳做法与数据协调核心密切合作， 样品跟踪和储存，支持两个岩芯之间的技术进程，以及 协调编码、运输、加工、接收、保存和转让标本的程序 生物检疫和研究数据到NIDDK中央数据和标本储存库。 具体目标3：继续参加工作组和数据分析和手稿 支持MAPP-RN的准备工作。我们将继续参与MAPP的执行和指导 委员会会议和电话会议。我们将继续作为MAPP RN工作组的积极参与者 在想法和假设开发、数据分析和手稿准备方面进行协作。

The TATC at the University of Colorado will continue to provide expertise and resources in support of the MAPP‐RN during the proposed MAPP‐Phase II extension period. The TATC was established to assist the MAPP‐RN with biospecimen collection, processing, and analyses. The TATC will work closely with the MAPP Executive and Steering Committees, the NIDDK, the Discovery Site Teams, and the Data Coordinating Core to ensure that the goals of the MAPP RN are met. The TATC will meet all NIH quality standards and will work closely with the DCC and the NIDDK Central Repository to coordinate eventual transfer of all residual biospecimens and ancillary data to the Central Repository before the end of the three‐year extension period. The current funding period ends in June 2019. We propose a three‐year funding extension, through June 2022 to accomplish the following: SPECIFIC AIM 1 Provide Biorepository Support to the MAPP RN. The TATC will continue to act as the central repository during the extended 12-month follow up window for all biospecimens collected in the SPS study and provide biospecimen collection kits, procedural guidance on specimen collection, handling, centralized processing, and archiving in support of MAPP-II. SPECIFIC AIM 2: Collaborate with the DCC on specimen-associated data collection and tracking. We will continue to closely collaborate with the Data Coordination Core (DCC) on best practices for data collection, specimen tracking and storage, and to support technical processes between the two cores, as well as coordinate procedures for coding, shipping, processing, receipt, storage of specimens, and the transfer of biospecimens and study data to the NIDDK Central Data and Specimen Repositories. SPECIFIC AIM 3: To continue participation in the Working Groups and in data analysis and manuscript preparation in support of MAPP-RN. We will continue to participate in the MAPP Executive and Steering committee meetings and calls. We will continue to be active partcipants in the MAPP RN Working Groups to collaborate on idea and hypothesis development, data analysis and manuscript preparation.