CSHL Conference on Germ Cells

项目摘要 生殖系是产生配子的细胞谱系，因此具有实质性的实用性和生物学意义。 学术意义。生殖细胞可以构成用于组织替代的干细胞来源， 它们的发展与生育和生殖问题有关。因此，除了在国家一级的兴趣之外， 基础科学，生殖细胞生物学的知识适用于医学和农业。最近的重大进展 这些领域是在不同模式生物和人类中建立的，这使得来自不同领域的研究人员 他们将聚集在一起分享和讨论他们的发现。 本提案寻求对两年期系列会议第十二、十三和十四次会议的支持， 在冷泉港实验室，这是该领域的首次会议。2020年生殖细胞会议将在 会议将于9月29日至10月3日举行，根据以往会议的出席情况，我们预计将有250-300人参加。 来自世界各地的参与者。生殖细胞研究的所有方面都没有竞争性的类似论坛。 平台展示的广泛主题包括控制生殖细胞的分子机制 生殖细胞分化为配子，生殖系干细胞， 减数分裂、表观遗传学和与人类生殖系相关的表现。会议将由专家主持 在相应的领域，为年轻科学家提供展示其工作的机会。此外，非常 简短的“专题讲座将向参加者介绍海报展示会的重点。足够的机会 还将确保非正式互动。

Project Summary The germ line is the cell lineage that gives rise to gametes and as such is of substantial practical and scholarly significance. Germ cells can constitute a source of stem cells for tissue replacement, and understanding their development is relevant for fertility and reproduction issues. Thus, in addition to the interest at the level of the basic science, knowledge of germline biology is applicable for medicine and agriculture. Recent major advances in the field were made in different model organisms and in human making it critical that researchers from diverse arenas be brought together to share and discuss their discoveries. This proposal seeks support for the twelfth, thirteenth and fourteenth of a biennial series of meetings held at Cold Spring Harbor Laboratory that is the premiere meeting for this field. The 2020 Germ Cells meeting will be held on September 29th-October 3rd and based on the attendance at previous meetings we expect to 250-300 participants from around the world. There are no competing similar forums for all aspects of germ cell research. Broad topics for platform presentations include the molecular mechanisms controlling germ cell specification and the control over the germ-cell fate, germ cell differentiation into gametes, germline stem cells, meiosis, epigenetics, and presentations relevant for the human germline. The sessions will be chaired by experts in the corresponding fields, providing young scientists with the opportunity to present their work. In addition, very short “flash talks” will provide the participants with highlights from the poster sessions. Ample opportunity for informal interactions will also be ensured.