Psychosocial Stress and Adaptation to the COVID-19 Pandemic in the Latinx Population

项目总结 在美国的拉美裔美国人受到经济、健康和心理社会的不成比例的影响 与新冠肺炎大流行有关的压力源。然而，这些人口仍然没有得到充分的研究和服务 目前的研究。目前的项目旨在通过研究加州家庭项目的成年人来填补这一空白 (CFP)，这是一项对墨西哥裔成年人的长期纵向研究，他们被纵向跟踪了 超过14年的中年(在本拟议补编中约为N=900)。目的 本补编下的拟议研究是为了增加(A)新冠肺炎相关压力的评估 暴露和行为，(B)认知和身体健康的额外评估，和(C)新冠肺炎 CFP参与者的抗体测试。为了达到这一目标，研究小组将开展两项具体工作 目标。首先，我们将确定认知、社会经济、个性和社会/关系预测因素 测试与新冠肺炎相关的压力负担，并测试与新冠肺炎相关的压力是否与 认知功能和身体健康。对于第二个目标，我们将测试大流行前的认知， 新冠肺炎预防依从性的社会经济、个性和社会/关系预测因素 措施(例如，戴口罩、社交距离)和接种意愿。我们还将测试其程度 对预防措施的遵从性预测身体健康结果，如新冠肺炎 实验室免疫球蛋白抗体检测所反映的感染。实现这些目标将使我们能够 与大流行相关的累积应激负担对同期和长期的不利影响 认知功能和阿尔茨海默病风险的轨迹，以及识别风险和复原力因素 在这个人口中。此外，对认知、社会经济、个性和社会/关系的分析 新冠肺炎预防措施遵从性和接种意愿的预测因素 新冠肺炎将直接告知公共卫生努力，以减少当前和 对于特别脆弱的人群来说，未来的大流行。

PROJECT SUMMARY Latinos in the United States have been disproportionately affected by the economic, health, and psychosocial stressors related to the COVID-19 pandemic. Yet this population remains understudied and underserved in current research. The current project aims to fill this gap by studying adults from the California Families Project (CFP), a long-standing longitudinal study of Mexican-origin adults who have been followed longitudinally for over 14 years across middle adulthood (approximate N = 900 in this proposed supplement). The purpose of the proposed research under this supplement is to add (a) an assessment of COVID-19-related stress exposure and behavior, (b) an additional assessment of cognition and physical health, and (c) a COVID-19 antibody test for participants in the CFP. To meet this objective, the research team will undertake two specific aims. First, we will identify cognitive, socioeconomic, personality, and social/relational predictors of cumulative stress burden related to COVID-19 and test whether COVID-19-related stress is associated with declines in cognitive function and physical health. For the second aim, we will test pre-pandemic cognitive, socioeconomic, personality, and social/relational predictors of compliance with COVID-19 prophylactic measures (e.g., mask wearing, social distancing) and willingness to be vaccinated. We will also test the extent to which compliance with prophylactic measures predicts physical health outcomes, such as COVID-19 infection as reflected by a laboratory IgG antibody test. Accomplishing these aims will allow us to characterize the detrimental effects of cumulative stress burden related to the pandemic on concurrent and long-term trajectories in cognitive function and risk for Alzheimer’s disease, as well as identify risk and resilience factors within this population. Furthermore, analyses of the cognitive, socioeconomic, personality, and social/relational predictors of compliance with COVID-19 prophylactic measures and of willingness to be vaccinated against COVID-19 will directly inform public health efforts to reduce the adverse consequences of the current and future pandemics for a particularly vulnerable population.