Stanford Molecular Imaging Scholars (SMIS) Program

项目摘要/摘要 斯坦福大学分子成像学者(SMIS)项目是一个综合的、为期3年的跨学科项目 斯坦福大学博士后培训项目，汇集了13名教师导师中的30名 医学院、工程学院、人文和科学学院的系。分子成像(MI)， 一种非侵入性技术，用于可视化和量化生活中特定的分子和生化过程 生物体，使医学和生物医学研究发生了革命性的变化，并继续扩大其在 癌症的检测、治疗和管理。继续进步和发展的关键 重要领域是深入培养下一代癌症MI科学家。我们建议培训7名 每年博士后实习生(包括一年级、二年级和三年级研究员)。SMIS教职员工导师和广泛的 资源，提供丰富多样的培训环境，涵盖生物、物理、 数学、生物计算/生物医学信息学、工程、化学、生物化学、癌症生物学、 免疫学和医学。SMIS计划的核心是为受训人员提供机会(包括 博士、医学博士或医学博士/博士学位)进行创新的MI研究，该研究由 研究和临床学科的互补性。SMIS学员还从事专门的课程工作， 研讨会、国家会议、临床查房，包括负责任地进行研究的道德培训， 和增强研究的再现性。为期3年的计划以准备和 提交一份NIH拨款提案，以支持受训人员过渡到癌症MI的独立职业生涯。 在前三个授予周期中，有39名学员参加了SMIS方案；目前已有5名学员报名参加 截至撰写本文时，已有34家公司完成了该计划。那些已经离开的人要么是教职员工，要么是其他 学术职位，或在生物技术领域工作。对中小企业培训的需求很高；我们现在 平均每年收到10份或更多来自合格候选人的申请，每个职位有2-3个新的实习生职位 年。对于即将到来的周期，我们在以下几个方面提出了丰富的SMIS计划：扩大MI 程序区定义明确包括体内细胞跟踪、免疫治疗和治疗，以及 计算；额外多样化导师的战略选择；所有培训和职业生涯的改进 发展部分；为我们的培训委员会扩大女性领导力，赠款撰写提案 活动、临床暴露部分和招募代表不足的少数族裔候选人。这个 SMIS计划的持续目标是为有才华的年轻研究人员提供科学和 专业教育/职业发展机会，成为该领域的领导者。

PROJECT SUMMARY/ABSTRACT The Stanford Molecular Imaging Scholars (SMIS) program is an integrated, 3-year cross-disciplinary postdoctoral training program at Stanford University that brings together 30 faculty mentors from 13 departments in the Schools of Medicine, Engineering, and Humanities and Sciences. Molecular imaging (MI), a noninvasive technique to visualize and quantify specific molecular and biochemical processes in living organisms, has revolutionized medicine and biomedical research, and continues to expand its applications in the detection, treatment, and management of cancer. Key to the continued advancement and growth of this important field is the in-depth training of the next generation of cancer MI scientists. We propose to train 7 postdoctoral trainees per year (comprising 1st, 2nd, and 3rd year fellows). SMIS faculty mentors, and extensive resources, provide a rich and diverse training environment spanning fields such as biology, physics, mathematics, biocomputations/biomedical informatics, engineering, chemistry, biochemistry, cancer biology, immunology, and medical sciences. The centerpiece of the SMIS program is the opportunity for trainees (with PhD, MD, or MD/PhD degrees) to conduct innovative MI research that is co-mentored by faculty in complementary research and clinical disciplines. SMIS trainees also engage in specialized coursework, seminars, national conferences, clinical rounds, including ethics training in the responsible conduct of research, and enhancement of research reproducibility. The 3-year program culminates with the preparation and submission of an NIH grant proposal, in support of trainee transition to an independent career in cancer MI. During the previous three award cycles, 39 trainees have entered the SMIS program; 5 are currently enrolled and 34 have completed the program as of this writing. Those who have moved on are either in faculty or other academic positions, or working in the biotechnology field. Demand for the SMIS training is high; we now receive, on average, 10 or more applications per year from qualified candidates for 2-3 new trainee slots per year. For the upcoming cycle, we propose an enriched SMIS program in the following aspects: expansion of MI program area definitions to explicitly include cell tracking in vivo, immunotherapy and theranostics, and computations; strategic selection of additional diverse mentors; improvement in all training and career development components; expansion of female leadership for our training committee, grant writing proposal activity, clinical exposure components, and recruitment of underrepresented minority candidates. The continued goal of the SMIS program is to provide talented young researchers with the scientific and professional educational/career development opportunities to become leaders in the field.