Regulatory Science in Environmental Health and Toxicology

项目描述 环境卫生与毒理学监管科学 该提案是为了继续“环境健康和毒理学监管科学”中的T32计划。 德州农工大学的毕业生资金被要求支持八个博士前（博士）。候选人）和两个职位- 在现有的高度一体化的学位授予毒理学跨学科学院的博士生 程序.我们的目标仍然是准备学员作为独立的研究人员和/或从业人员在一个 多学科环境，提供机械研究和风险评估方面的培训，重点是 对药物和其他化学品对人体的影响进行科学合理的、基于风险的监管评估 健康和环境。为了实现这一目标，由以下人员组成的团队提供教学和研究经验 20名杰出的研究人员谁专门从事机械毒理学，社区参与，暴露 评估/环境化学、公共政策、流行病学、生物医学工程和数据科学 和模特。招聘是通过传统的外部广告和专业协会进行的， 以及现有的一些为本科生提供研究经验的德克萨斯A&M项目， 以及公共卫生和毒理学硕士级培训。博士前实习生承担两个实验室 在项目的第一年进行轮换，并遵循结构化的核心学术课程，其中包括基本的 先进的毒理学、组织病理学、药理学、生物统计学和研究伦理学， 风险评估和暴露评估课程。在第二年，额外的专业培训是 通过选修课程提供，进一步培养学员从事研究和/或公共卫生事业 实践该计划的显着特点是（一）强烈鼓励动手夏季校外通过 一个由州和联邦政府监管机构、公司和非政府组织组成的广泛而多样化的网络， 政府组织;以及（ii）以靴子训练营和特别 针对学员选择的广泛主题（科学写作、演讲、面试技巧、灾难）举办研讨会 研究和数据科学）。在头两年之后，为博士前和博士后研究员提供培训支持 转向他们的导师或独立资助。所有的导师都有强大的竞争支持记录， 联邦、州和其他来源，这一组导师在相关的 科学专长、性别和学术生涯水平。该计划的毕业生在以下方面非常成功： 学术界，并在行业，政府机构和其他专业设置的雇主追捧。 我们的学员通过创新和严格的机制研究和风险管理， 评估实践，以支持严格的基于科学证据的监管决策。

PROJECT DESCRIPTION Regulatory Science in Environmental Health and Toxicology This proposal is to continue the T32 program in “Regulatory Science in Environmental Health and Toxicology” at Texas A&M University. Funds are requested to support eight pre-doctoral (Ph.D. candidates) and two post- doctoral trainees in the existing highly integrated degree-granting Interdisciplinary Faculty of Toxicology program. Our goal remains to prepare trainees to function as independent researchers and/or practitioners in a multidisciplinary setting, by providing training in mechanistic research and risk assessment with a focus on scientifically sound, risk-based regulatory evaluations of the effects of drugs and other chemicals on human health and the environment. To achieve this goal, didactic and research experiences are offered by a team of 20 outstanding investigators who specialize in mechanistic toxicology, community engagement, exposure assessment/environmental chemistry, public policy, epidemiology, biomedical engineering, and data science and modeling. Recruitment is conducted through traditional external advertisement and professional societies, as well as from a number of existing Texas A&M programs that offer research experience for undergraduates, and public health and toxicology masters-level traineeship. Pre-doctoral trainees undertake two laboratory rotations in their first year in the program and follow a structured core academic curriculum that includes basic and advanced toxicology, histopathology, pharmacology, biostatistics and research ethics, combined with courses in risk assessment and exposure assessment. In the second year, additional specialized training is offered through elective courses that further prepare trainees for careers in research and/or public health practice. Distinctive features of the program are (i) a strongly encouraged hands-on summer externship through a broad and diverse network of state and federal governmental regulatory agencies, companis and non- governmental organizations; and (ii) a series of special programs in the form of boot camps and special workshops on a wide range of trainee-selected topics (scientific writing, presentation, interview skills, disaster research and data science). Following the first two years, trainee support for both pre- and post-doctoral fellows shifts to their mentor’s or independent funding. All mentors have strong records of competitive support from Federal, State and other sources and this group of mentors is exceptionally well balanced with respect to relevant scientific expertise, sex and academic career level. Graduates from the program are highly successful in academia, and sought-after by employers in the industry, governmental agencies and other professional settings. Our trainees improve public health protection through innovative and rigorous mechanistic research and risk assessment practice in support of rigorous scientific evidence-based regulatory decision-making.