NICHD Neonatal Research Network -- Cincinnati Clinical Center

项目摘要 NICHD新生儿研究网络（NRN）的建立是为了对新生儿进行严格的研究。 医学，促进中心之间的合作，以比研究者更快地完成研究。 一个人辛辛那提儿童医院医疗中心一直是NRN最具生产力的网站之一， 超过30年我们的网站的强劲表现是由于我们的大，多样化的患者群体，突出 研究基础设施和临床设施，强大的教师研究人员在各种各样的专业知识， 新生儿研究和经验丰富的研究支持人员。我们的领导层明白， 大型多中心试验，以回答生殖医学的临床问题。Stephanie Merhar博士，校长 辛辛那提研究中心的研究者，已在辛辛那提领导NRN研究和其他多中心试验超过7年 年Tanya Cahill博士作为随访主要研究者和Vivek博士加入了此次更新 纳伦德朗和金载作为候补私家侦探在下一个周期，辛辛那提将与其他国家合作， 临床中心、外部研究者和数据协调中心制定和实施严格的 和可再现的通用协议。由于我们独特的区域性、基于人口的护理模式， 在我们的3个新生儿重症监护室中，每年有超过1900名新生儿重症监护室入院，我们能够贡献大量的 NRN观察性研究和临床试验的受试者。我们完善的区域跟进 基础设施使我们能够最大限度地提高22-26个月和学龄随访的保留率。我们 致力于通过NRN进行确定性的多中心临床研究，以改善 早产和其他严重情况的新生儿。

PROJECT SUMMARY The NICHD Neonatal Research Network (NRN) was established to conduct rigorous research in neonatal medicine, facilitating collaboration among centers to complete studies more rapidly than investigators acting alone. Cincinnati Children’s Hospital Medical Center has been one of the most productive sites in the NRN for over 30 years. Our site’s strong performance is due to our large, diverse patient population, outstanding research infrastructure and clinical facilities, strong faculty investigators with expertise in a wide variety of neonatal research, and experienced research support staff. Our leadership understands the importance of large, multicenter trials to answer clinical questions in neonatology. Dr. Stephanie Merhar, Principal Investigator for the Cincinnati site, has led NRN studies and other multicenter trials in Cincinnati for over 7 years. She is joined for this renewal by Dr. Tanya Cahill as Follow-up Principal Investigator and Drs. Vivek Narendran and Jae Kim as alternate PIs. During this next cycle, Cincinnati will work collaboratively with other Clinical Centers, outside investigators, and the Data Coordinating Center to develop and implement rigorous and reproducible common protocols. Due to our exceptional model of regional, population-based care with more than 1900 annual NICU admissions in our 3 recruiting NICUs, we are able to contribute a large number of subjects to NRN observational studies and clinical trials. Our well-established regional follow up infrastructure allows us to maximize retention rates for both 22-26 month and school age follow up. We are committed to conducting definitive multi-site clinical research through the NRN to improve outcomes for newborns born preterm and with other serious conditions.