Administrative Supplement: 1/2 Trans-ancestry genomic analysis of obsessive-compulsive disorder
Administrative Supplement: 1/2 Trans-ancestry genomic analysis of obsessive-compulsive disorder
批准号:
10818832
负责人:
James Joseph Crowley
金额:
$7.13万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-09-01 至 2026-06-30
关键词:
AccelerationAdministrative SupplementAfrican ancestryAnhedoniaAsianCognitionCommunitiesConsensusCountryDataData AnalysesData AnalyticsData CollectionDepositionDiagnosisDiscriminationEnvironmental Risk FactorEquityFutureGeneticGenomicsGoalsHealthcare SystemsIndividualLatin AmericanLatinx populationMeasurementMeasuresMental HealthMental disordersNational Institute of Mental HealthObsessive compulsive behaviorObsessive-Compulsive DisorderPhenotypePopulationPopulation HeterogeneityProceduresProcessPropertyPsychometricsReproducibilityResourcesRiskSiteStandardizationSymptomsUnderrepresented Populationscognitive functioncohortdata archivedisease phenotypeinstrumentmemberphenotypic datapsychogeneticssocial stigmasuicidaltrait
中文摘要
项目摘要
该项目实现了祖先人口网络(APN; PAR-20-026和PAR-20- 027)的一个主要目标。
027),即促进APN成员之间的测量和数据分析协调工作,
严谨性和可重复性,并为网络成员和科学界提供资源。通过
APN成员的共识过程,快感缺乏,认知,强迫症状,
自杀倾向和歧视/污名被选择用于协调正在进行的研究。这些
将在代表亚洲、拉丁美洲和加勒比地区的大约27,500名个人中收集统一的测量数据,
美国和非洲血统跨越15个国家。
英文摘要
PROJECT SUMMARY
This project actualizes a primary goal of the Ancestral Populations Network (APN; PAR-20-026 and PAR-20-
027), namely to facilitate measurement and data analytic harmonization efforts across APN members to enhance
rigor and reproducibility and generate a resource for network members and the scientific community. Through a
consensus process of APN members, measures of anhedonia, cognition, obsessive-compulsive symptoms,
suicidality, and discrimination/stigma were selected for harmonization across ongoing studies. These
harmonized measures will be collected across an estimated 27,500 individuals representing Asian, Latin
American, and African ancestries spanning over 15 countries.
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
Genomics of Obsessive-Compulsive Disorder and Related Disorders: What the Clinician Needs to Know.
强迫症和相关疾病的基因组学:临床医生需要了解的内容。
DOI:
10.1016/j.psc.2022.11.003
发表时间:
2023-03
期刊:
PSYCHIATRIC CLINICS OF NORTH AMERICA
影响因子:
1.7
作者:
[Crowley, James J.]
通讯作者:
Crowley, James J.
Latin American Trans-ancestry INitiative for OCD genomics (LATINO): Study Protocol.
拉丁美洲跨祖先强迫症基因组学倡议 (LATINO):研究方案。
DOI:
10.1101/2023.02.23.23286373
发表时间:
2023
期刊:
medRxiv : the preprint server for health sciences
影响因子:
--
作者:
[Crowley,JamesJ, Cappi,Carolina, Ochoa-Panaifo,MarcosE, Frederick,ReneeM, Kook,Minjee, Wiese,AndrewD, Rancourt,Diana, Atkinson,ElizabethG, Giusti-Rodriguez,Paola, Anderberg,JaceyL, LatinAmericanTrans-ancestryINitiativeforOCDgenomics(]
通讯作者:
LatinAmericanTrans-ancestryINitiativeforOCDgenomics(
1/2 Trans-ancestry genomic analysis of obsessive-compulsive disorder
-
批准号:10261855
-
项目类别:
-
资助金额:$32.79万
-
财政年份:2021
-
负责人:James Joseph Crowley
-
依托单位:
1/2 Trans-ancestry genomic analysis of obsessive-compulsive disorder
-
批准号:10646445
-
项目类别:
-
资助金额:$30.48万
-
财政年份:2021
-
负责人:James Joseph Crowley
-
依托单位:
1/2 Trans-ancestry genomic analysis of obsessive-compulsive disorder
-
批准号:10478300
-
项目类别:
-
资助金额:$30.94万
-
财政年份:2021
-
负责人:James Joseph Crowley
-
依托单位:
2/2 Rare Genetic Variation and Risk for Obsessive Compulsive Disorder
-
批准号:10516725
-
项目类别:
-
资助金额:$19.44万
-
财政年份:2020
-
负责人:James Joseph Crowley
-
依托单位:
2/2 Rare Genetic Variation and Risk for Obsessive Compulsive Disorder
-
批准号:10318565
-
项目类别:
-
资助金额:$7.78万
-
财政年份:2020
-
负责人:James Joseph Crowley
-
依托单位:
2/2 Rare Genetic Variation and Risk for Obsessive Compulsive Disorder
-
批准号:10095318
-
项目类别:
-
资助金额:$7.78万
-
财政年份:2020
-
负责人:James Joseph Crowley
-
依托单位:
Investigating the molecular mechanisms and consequences of assortative mating in major psychiatric disorders: completing a missing piece of the psychiatric genetics puzzle
-
批准号:9545065
-
项目类别:
-
资助金额:$14.42万
-
财政年份:2017
-
负责人:James Joseph Crowley
-
依托单位:
OCD: Novel Comparative Genomic Approaches to Identify Disease and Treatment Mechanisms
-
批准号:10161830
-
项目类别:
-
资助金额:$59.52万
-
财政年份:2016
-
负责人:James Joseph Crowley
-
依托单位:
OCD: Novel Comparative Genomic Approaches to Identify Disease and Treatment Mechanisms
-
批准号:9691493
-
项目类别:
-
资助金额:$60.12万
-
财政年份:2016
-
负责人:James Joseph Crowley
-
依托单位:
OCD: Novel Comparative Genomic Approaches to Identify Disease and Treatment Mechanisms
-
批准号:9156382
-
项目类别:
-
资助金额:$65.09万
-
财政年份:2016
-
负责人:James Joseph Crowley
-
依托单位:
Genetic & Environmental Predictors of Tourette Syndrome & OCD in Denmark
-
批准号:8801163
-
项目类别:
-
资助金额:$64.53万
-
财政年份:2015
-
负责人:James Joseph Crowley
-
依托单位:
Genetic & Environmental Predictors of Tourette Syndrome & OCD in Denmark
-
批准号:9186005
-
项目类别:
-
资助金额:$60.42万
-
财政年份:2015
-
负责人:James Joseph Crowley
-
依托单位:
Finding single-gene copy number variants in schizophrenia
-
批准号:8771896
-
项目类别:
-
资助金额:$22.8万
-
财政年份:2014
-
负责人:James Joseph Crowley
-
依托单位:
Systems Genetics of Fluoxetine-Induced Neurogenesis and Antidepressant Response
-
批准号:8619660
-
项目类别:
-
资助金额:$15.67万
-
财政年份:2012
-
负责人:James Joseph Crowley
-
依托单位:
Systems Genetics of Fluoxetine-Induced Neurogenesis and Antidepressant Response
-
批准号:8433355
-
项目类别:
-
资助金额:$15.67万
-
财政年份:2012
-
负责人:James Joseph Crowley
-
依托单位:
Systems Genetics of Fluoxetine-Induced Neurogenesis and Antidepressant Response
-
批准号:8815333
-
项目类别:
-
资助金额:$11.82万
-
财政年份:2012
-
负责人:James Joseph Crowley
-
依托单位:
Systems Genetics of Fluoxetine-Induced Neurogenesis and Antidepressant Response
-
批准号:8300480
-
项目类别:
-
资助金额:$15.67万
-
财政年份:2012
-
负责人:James Joseph Crowley
-
依托单位:
海外基金