Advanced Development of Universal Vaccines for Influenza

该项目的主要目标是支持在故意释放或应对自然发生的传染病暴发之后，在事后环境中使用的候选产品的高级开发。该合同可能支持单独疫苗成分的配方和制造，以及稳定性测试、非人类灵长类动物的非临床免疫原性和有效性测试、启用GLP重复剂量毒理学的IND、提交IND和最终的临床评估。

The primary objective of this project is to support the advanced development of candidate products for use in post-event settings following the intentional release of or in response to naturally occurring outbreaks of infectious diseases. This contract may support formulation and manufacture of the individual vaccine components, as well as stability testing, nonclinical immunogenicity and efficacy testing in nonhuman primates, IND enabling GLP repeated dose toxicology, submission of an IND and eventual clinical evaluation.