NOVEL FAST TIMING SILICON DRIFT PHOTODETECTORS FOR PET

该提案的目标是开发一种新型探测器/成像 用于正电子发射成像的装置。 基本探测器模块将 由切割成平行管元件的LSO晶体组成， 耦合到匹配的硅漂移光电探测器（SDP）阵列 其元件提供优良的能量和定时分辨率。 拟议的系统旨在消除 光电倍增管，并允许电子集成， 该探测器导致更低成本的PET系统。 我们计划 开发一种成像系统，利用一对4英寸直径的 LSO/SDP模块，每个模块由40 x 40探测器像素组成， 优化与FDG一起用于检测乳腺癌。 一 为乳房成像而优化的符合成像装置具有 提高灵敏度（x20）、计数率和 空间分辨率与完整PET系统。 的发展 2探测器模块乳房成像器将允许基本探测器 发展沿着需要的发展 提高癌症检测的产品。 提高灵敏度将 导致更好的图像质量、减少成像时间或更小 注射剂量。 拟议的探测器开发计划 具体目标分为两个技术阶段。 第1阶段：设计 优化探测器结构，实现目标性能 对于电子噪声，量子效率， 电子;（2）制作原型8 x 8 SDP阵列;（3）评估 衡量成功潜力的设计参数， 项目的长期目标。 阶段2：（1）制定最终SDP 具有集成输入晶体管的阵列结构;（2） 发展住宅、专业化加工和显示电子产品， 重建软件;（3）原型的构建和评估 检测器系统在模拟临床条件下， 在UCLA Iris Cantor乳腺中心进行测试。 建议的商业应用 在第三阶段，我们将商业化的单一和多个 基于第1阶段和第2阶段工作的探测器模块， 以及一个完整的专用系统，用于临床使用的正电子 用于检测乳腺癌的发射成像。 这些新 探测器将导致更低成本的PET探测器系统， 一种只需要低成本硅平面处理的新SDP， 允许将电子器件与检测器集成。 有大型 这种PMT商业用途的需求和潜力 PET的替代品

The goal of this proposal is to develop a novel detector/imaging device for positron emission imaging. A basic detector module will consist of an LSO crystal cut into parallet-piped elements and coupled to a matched Silicon Drift Photodetector (SDP) array whose elements provide excellent energy and timing resolution. The proposed system is intended to eliminate the need for photomultiplier tubes and allow for intergration of electronics with the detector leading to lower cost PET systems. We plan to develop an imaging system utilizing a pair of 4 inch diameter LSO/SDP modules, each consisting of 40 x 40 detector pixels, optimized for use with FDG for detection of breast cancer. A coincidence imaging device optimized for breast imaging has the potential of improving on the sensitivity (x20), count rate and spatial resolution versus a full PET system. The development of the 2-detector module breast imager will allow basic detector development to occur along with the development of a needed product to improve cancer detection. Improved sensitivity will result in better image quality, reduced imaging time or smaller injected doses. The proposed detector development program has specific goals divided into two technical phases. Phase 1: Design optimized detector structure leading to the targeted performance for electronic noise, quantum efficiency, narrow transit time of electrons; (2) Fabricate prototype 8 x 8 SDP array; (3) Evaluate parameters of the devise to measure the potential for success for long term aims of the project. Phase 2: (1) Develop final SDP array structures with integrated input transistor-preamplifier; (2) Develop housing, specialized processing and display electronics and reconstruction software; and (3) Construct and evaluate prototype detector system under simulated clinical conditions before deployment for testing at the UCLA Iris Cantor Breast Center. PROPOSED COMMERCIAL APPLICATION In the third phase we will commercialize single and multiple detector modules based upon the Phase 1 and Phase 2 efforts, as well as a complete dedicated system for clinical use in positron emission imaging for detection of breast cancer. These new detectors will lead to lower cost PET detector systems by utilizing a new SDP which needs only low cost silicon planar processing and allows integration of electronics with the detector. There are large needs and potential for commercial uses for such PMT replacements for PET.