RAPID,ROBUST AND AUTOMATED CONTIN CARDIAC OUTPUT SYSTEM

描述(改编自申请者摘要)：这是第一阶段 双热敏电阻在新型导管研制中的应用 以及用于连续(实际上是频繁地)的加热元件 间歇性的)心输出量的测量。在控制期内 如果不加热，两个热敏电阻之间的任何温差都是 进行测量和积分，以便随后进行温度校正 在放置的元件的加热期间记录的差值 在两个热敏电阻之间。 该项目的具体目标是(1)开发和制造特殊的 导管、微处理器控制的仪器和软件(2) 在试验台上对系统进行分析和验证；(3)在 4头猪。 新系统声称的具体优势是，它将对 对心输出量变化的反应比目前的Baxter或 雅培系统，它将能够忽略 深层体温变化相对较快，例如发生在 从体温过低中恢复。衡量成功的标准包括准确性和 重复的速度。

DESCRIPTION (Adapted from applicant's abstract): This is Phase I application for the development of a new catheter with two thermistors and a heating element for the continuous (actually frequently intermittent) measurement of cardiac output. During a control period without heating, any temperature difference between the two thermistors is measured and integrated for subsequent correction of the temperature difference recorded during the period of heating of an element placed in between the two thermistors. The specific aims of the project are (1) to develop and fabricate special catheters, microprocessor controlled instrumentation and software (2) to analyze and validate the system on the bench and (3) to test the system in 4 pigs. Specific advantages claimed for the new system are that it will respond much faster to changes in cardiac output than the current Baxter or Abbott systems and that it will be able to ignore the effects of relatively fast changes in deep body temperature, such as occur during recovery from hypothermia. Measures of success consist of accuracy and speed of repetition.