FAST DUAL PATH SYSTEM FOR RESPIRATORY GAS ANALYSIS

拟议的第一阶段研究的目标是确定可行性 一种用于呼吸气体分析的快速双路径系统。应用 用于医疗保健和生理评估中的呼吸道气体分析 和众多而重要的，包括新陈代谢的测量，肺 通风效率和病人监护。这项研究提出 开发一种结合了独特的氧气方法的系统 基于顺磁性和声学方法的分析 测定任何给定氧气水平的二氧化碳。对经济发展至关重要 提出的研究内容是高速的开发和实现 气动开关，可快速互换试验和环境气体 换能器(顺磁和声学)，从而提供卓越的 稳定性。将对生成的第一阶段原型进行动态评估 响应性、线性、基线稳定性和量表稳定性。它 预计由此产生的呼吸气体分析器将具有 响应时间为&lt；75毫秒，并将能够逐一呼吸 分析。拟议的发展将导致新一代 性能卓越的呼吸气体分析器 显著节省成本。最终O2/CO2分析仪的估计成本 在750美元到1000美元之间。 拟议的商业应用：呼吸系统气体分析广泛应用 在保健环境和生理方面的研究。氧气和 二氧化碳分析器通常作为独立的分析器或 结合在新陈代谢测量系统或麻醉监测仪中。 每年售出数以千计的呼吸气体分析仪，而且有 过去在关键传感技术方面进展甚微 几年了。拟议发展项目的商业潜力是 重要的主要是高水平的性能以及 显著降低了成本。

The goal of the proposed Phase I research is to determine the feasibility of a fast dual path system for respiratory gas analysis. Applications for respiratory gas analysis in health care and physiological assessment and numerous and important, including the measurement of metabolism, lung ventilation efficiency, and patient monitoring. This research proposes development of a system that incorporates a unique method of oxygen analysis based on paramagnetism coupled with an acoustic method to determine carbon dioxide for any given level of oxygen. Essential to the proposed research is development and implementation of high speed pneumatic switching to rapidly interchange test and ambient gas in each transducer (paramagnetic and acoustic), thus providing exceptional stability. The resulting Phase I prototype will be evaluated for dynamic response, linearity, stability of baseline, and stability of scale. It is anticipated that the resulting respiratory gas analyzer will have a response time of <75 ms, and will be capable of breath-by-breath analysis. The proposed development will lead to a new generation of respiratory gas analyzers exhibiting superior performance together with significant cost savings. The estimated cost of the final O2/CO2 analyzer is between $750 - $1,000. PROPOSED COMMERCIAL APPLICATION: Respiratory gas analysis is widespread in the health care environment and physiological research. Oxygen and carbon dioxide analyzers are commonly found as stand-alone analyzers or combined in metabolic measurement systems or anesthetic monitors. Thousands of respiratory gas analyzers are sold each year, and there has been little progress in the critical sensing technologies over the past few years. The commercial potential of the proposed development is significant primarily for the high level of performance coupled with significantly reduced cost.