Multidisciplinary Research Training in Lung Biology

描述(由申请人提供)： 这项申请是为一项多学科研究培训拨款，以支持肺和重症监护医学部(PCCM)的一个长期项目，该项目将由现任主任Peter Wagner博士指导。它的目的是为经过精心挑选的内科科学家实习生在肺部生物学、健康和疾病的学术研究方面的职业生涯做准备，并将在他们3年奖学金的18个月研究部分期间为他们提供支持。该项目有12名研究员(每年4名)，我们要求提供6个博士后职位。这项提议的核心将继续是让受训人员直接参与研究，在有经验的基础和临床科学家的指导下，他们在培训过程中有富有成效的、有资金支持的调查方案和经验。研究培训机会分为三个重点领域，提供相当深入的培训和调查-1)肺血管生物学；2)呼吸道生物学(每个领域都提供基础和临床实验室研究)；以及3)以患者为导向的研究，后者提供公共卫生硕士学位选项。核心教员(20名成员)主要由从筹委会部门挑选出来的调查人员组成。一些与PCCM建立了联系的核心教员来自其他部门，甚至来自圣地亚哥州立大学。它们为该项目提供了强大的多学科组成部分，拥有资金支持的研究和经过证明的研究、培训和生产力方面的记录。这25名辅助教员将进一步增强多学科的可能性，他们包括：1)初级PCCM教员，他们将被指导成为未来的核心教员；2)主要是临床教员，他们将为我们的实习生研究的许多患者/疾病提供协作接口；3)PCCM以外的教员，他们可以支持特定的研究领域和方法，但由于他们的主要任命或研究兴趣，他们也与其他项目相关。该研究项目将由一个由安迪·里斯博士共同主持的研究培训委员会直接监督， 以患者为中心的研究副主任和基础研究副主任Jason袁博士。由Peter Fedullo博士担任主席的临床培训委员会将协调临床培训(不受这笔赠款的支持)，由Wagner博士(成员为Ries、袁和Fedullo)担任主席的执行研究员委员会将监督整个三年计划。特别注意通过正规课程进行研究的道德行为；指导研究员和初级教员；以及招聘代表性不足的少数群体(2003年四名新入职研究员中有一名是非洲裔美国人)。

DESCRIPTION (provided by applicant): This application is for a multidisciplinary research training grant to support a longstanding program in the Pulmonary and Critical Care Medicine Division (PCCM), to be directed by its current Chief, Dr. Peter Wagner. Its purpose is to prepare carefully selected physician scientist trainees for careers in academic research in lung biology, health, and disease and will support them during the 18 months research component of their 3 year fellowship. With 12 fellows in the program (4 per year), we request six postdoctoral positions. The centerpiece of this proposal will continue to be the direct involvement of trainees in research, under the preceptorship of experienced basic and clinical scientists with a record of productive, funded investigative programs and experience in the training process. The research training opportunities are divided into three focus areas that offer substantial depth in training and investigation - 1) pulmonary vascular biology; 2) airway biology (each offering both basic and clinical laboratory research); and 3) patient-oriented research, the latter offering an MPH degree option. The Core faculty (20 members) consists largely of selected investigators from the PCCM Division. Some core faculty with established ties to PCCM come from other Divisions/Depts and even from San Diego State University. They provide a strong multidisciplinary component to the program with funded research and a proven track record of research training and productivity. The 25 Supporting faculty, who further enhance the multidisciplinary possibilities, are a combination of: 1) junior PCCM faculty who will be mentored to become future core faculty; 2) mostly clinical faculty who will provide the collaborative interface to many of the patients/diseases our trainees will study; and 3) faculty outside PCCM who are available to support particular areas and methods of research, but who, by virtue of their primary appointment or research interest, are also associated with other programs. The research program will be directly overseen by a research training committee cochaired by Dr. Andy Ries, Associate Director for Patient Oriented Research and Dr. Jason Yuan, Associate Director for Basic Research. A clinical training committee chaired by Dr. Peter Fedullo will coordinate clinical training (not supported by this grant), and an executive fellowship committee chaired by Dr. Wagner (members Ries, Yuan and Fedullo) will oversee the entire three year program. Special attention is given to ethical conduct of research through formal coursework; to mentoring fellows and junior faculty; and to recruitment of underrepresented minorities (one of four entering fellows in 2003 is African American).