VISION SCREENING IN PRESCHOOLERS/TOSU CLINICAL CENTER

这项提议是俄亥俄州立大学验光学院(TOSU)作为参与学龄前儿童视力(VIP)研究的五个VIP临床中心之一。VIP研究是一项前瞻性的临床研究，旨在开发一套有效和高效的筛查测试，以确定那些需要进一步视力护理的3岁和4岁儿童弱视、斜视和/或严重屈光不正，这些都是儿童早期普遍存在的严重视力障碍。为了实现这些目标，俄亥俄州哥伦布市将对至少1,359名参加VIP附属Head Start项目的3岁和4岁儿童进行一系列筛查测试。这套测试包括根据设计特点、有效性和对学龄前儿童的适用性而选择的测试，包括马萨诸塞州视力测试(MassVat)、一种形式的Lea符号远距离视力测试、随机点E(RDE)立体视锐度测试，以及使用尼康Retinomax的非睫状肌麻痹症自动屈光。这一系列测试将由Leay People(Head Start Parents)在Head Start站点进行，以确保筛查员的可用性，利用受益于儿童的既得利益者，并最大限度地将此模式应用于其他社区。每个筛查不合格或不能通过筛查的儿童，以及随机选择的通过筛查的儿童子组，都将在Tosu临床中心接受全面的眼睛检查。该检查将作为检测目标障碍的权威方法或黄金标准。检测目标疾病的灵敏度和特异度将单独和结合用于每个筛查电池测试。本申请证明：a)至少1,853名参加Head Start的儿童可以使用Tosu VIP参与临床中心，以及b)在Head Start现场进行视力筛查和进行黄金标准检查的设施和人员可用。VIP研究的基本原理、设计和方法的完整细节包含在VIP程序手册(MOP)中，该手册与VIP研究主席申请一起提交。

This proposal is for The Ohio State University, College of Optometry (TOSU) to serve as one of the five VIP Participating Clinical Centers in the Vision In Preschoolers (VIP) Study. The VIP Study is a prospective, clinical study designed to develop an effective and efficient battery of screening tests to identify those 3- and 4-year~old Head Start children in need of further vision care for amblyopia, strabismus, and/or significant refractive error, that are the prevalent, significant vision disorders of early childhood. To accomplish these goals, a battery of screening tests will be administered to at least 1,359 3- and 4-year old children enrolled in VIP Affiliated Head Start programs throughout Columbus, Ohio. The battery of tests consists of tests chosen for their design characteristics, validity, and applicability to the preschool population and includes the Massachusetts Visual Acuity Test (MassVat), a form of the Lea symbols visual acuity test at distance, the Random Dot E (RDE) test of stereoacuity, and noncycloplegic autorefraction using the Nikon Retinomax. The battery of tests will be administered at Head Start Sites by Lay People (Head Start parents) which ensures availability of screeners, utilizes persons with a vested interest in benefitting children, and maximizes the applicability of this model to other communities. Each child who fails the screening or is unable, and a randomly selected subset of children who pass the screening, will undergo a comprehensive eye examination at TOSU Clinical Center. The examination will serve as the definitive method, or Gold Standard, for detection of the target disorders. The sensitivity and specificity for detection of the target disorders will be determined for each of the screening battery tests alone, and in combination. This application documents: a) access of TOSU VIP Participating Clinical Center to at least 1,853 children enrolled in Head Start and b) that facilities and personnel are available for conducting vision screenings at the Head Start sites and for conducting Gold Standard Examinations. Complete details of the VIP Study rationale, design, and methods are contained in the VIP Manual of Procedures (MOP), which is submitted with the VIP Study chair application.