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Mechanisms by which varicella zoster virus and herpes simplex virus control host functions to enhance pathogenesis

Mechanisms by which varicella zoster virus and herpes simplex virus control host functions to enhance pathogenesis
水痘带状疱疹病毒和单纯疱疹病毒控制宿主功能增强发病机制
批准号:
nhmrc : GNT1088005
负责人:
A/Pr Barry Slobedman
金额:
$60.79万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 --

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中文摘要
翻译
水痘带状疱疹病毒和单纯疱疹病毒是在大多数人类人口中引起疾病的阿尔法疱疹病毒。这项建议将探讨这两种密切相关的疱疹病毒的疾病和发病机制的基础问题,重点是这些病毒如何控制宿主功能。特别是,我们将定义这些病毒与自然杀伤(NK)细胞反应之间的相互作用。
英文摘要
Varicella Zoster Virus and Herpes Simplex Virus are alpha-herpesviruses that cause diseases in a majority of the human population. This proposal will explore issues fundamental to disease and pathogenesis of these two closely related herpesviruses, focusing on how these viruses can control host function. In particular, we will define the interactions between these viruses and the natural killer (NK) cell response.
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Understanding the role of ongoing viral activity in herpes simplex virus latency
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  • 项目类别:
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  • 资助金额:
    $98.08万
  • 财政年份:
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  • 负责人:
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  • 依托单位:
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  • 项目类别:
    Project Grants
  • 资助金额:
    $39.76万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Barry Slobedman
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How does varicella zoster virus cause shingles and associated disease during infection of human ganglia?
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    nhmrc : GNT1063744
  • 项目类别:
    Project Grants
  • 资助金额:
    $39.76万
  • 财政年份:
    2014
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    A/Pr Barry Slobedman
  • 依托单位:
Defining a virally-encoded molecular switch between productive and latent phases of human cytomegalovirus infection.
  • 批准号:
    nhmrc : 1030707
  • 项目类别:
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  • 资助金额:
    $22.51万
  • 财政年份:
    2012
  • 负责人:
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