Clinical Core

临床核心的目的是为项目1-3提供生物标本和行为数据。这个 CORE由青少年和青年医学部主办，该部门已有38年的 对青少年和青壮年进行研究。该司在以下方面拥有丰富的经验： 招募和保留临床上感染艾滋病毒的高危青少年和青壮年以及成年人 试验，病例数约为3 000名艾滋病毒青年和150名艾滋病毒以上青年(其中30人处于过渡期 到成人护理)，12-24岁的护理人员和300多名成年人进行研究。核心位于青少年和 青年医学诊所，巴尔菲莫尔的青少年临床和研究中心 城市。该诊所最近将其空间扩大了一倍，以扩大与生殖道感染、艾滋病毒和健康相关的研究活动 差异临床试验。自1992年以来，P.I.一直得到独立资助，在不同的 在过去的16年里，他一直是联邦资助的合作研究的接受者 好几年了。核心研究人员在人体主体保护、HIPAA、良好临床方面训练有素 实践，以及生物危害标本的处理。该团队在招聘、留住和 保护人类主体，特别是未成年人。核心研究人员将负责收集 所有必需的生物样本，如泌尿生殖器拭子、宫颈拭子、血液和行为数据 通过音频计算机辅助面谈(ACASI)。我们的临床医生将进行生殖 健康检查，并提供诊断和管理。此外，临床咨询人员 将通过我们的预防和健康教育团队提供一级和二级预防。研究 人员将包括核心主任、研究协调员、研究外展专家和临床医生。 更多的研究和行政人员将提供支持。该团队将每周进行一次研究 召开团队会议，确保完成项目1、2和3的活动。这些会议将有 首席调查人员、实验室工作人员、临床和医学核心的参与。人类主体 保护和研究的适当性将由IRB进行监测，IRB是我们部门的研究特别工作组 和青年社区咨询委员会。我们网站的特点和成功研究的悠久历史 实施使我们唯一有资格执行项目1、2和3

The purpose of the Clinical Core is to provide biological specimens and behavioral data to Projects 1-3. The Core is hosted by the Division of Adolescent and Young Adult Medicine that has a 38 year history of conducfing research in adolescents and young adults. The Division has extensive experience in the recruitment and retenfion of at risk and HIV infected adolescents and young adults, and adults in clinical trials, with a case load of approximately 3,000 HIV-youths and 150 HIV+ youths (30 of who are in transition to adult care) ages 12-24 in care and over 300 adults in research. The Core is located at the Adolescent and Young Adult Medicine Clinic, a clinical and research center for adolescents and young adults In Balfimore City. The Clinic has recenfiy doubled its space to expand research activities related to RTIs, HIV, and health disparities clinical trials. The P.I. has been independently funded since 1992 to conduct studies in diverse populations and has been the recipient of federally funded collaborative research studies for the last 16 years. The Core research personnel are well trained in human subject protecfion, HIPAA, Good Clinical Pracfice, and handling of biohazard specimens. The team has expertise in the recruitment, retention and protecfion of human subjects, in particular minors. Core research personnel will be responsible for collecting all required biological samples such as genitourinary swabs, endocervical swabs, blood, and behavioral data through the Audio Computerized Assisted Interview (ACASI). Our clinicians will perform the reproductive health examinafions, and provide diagnosis and management. In addifion, the clinical counseling personnel will provide primary and secondary prevention through our prevenfion and health education team. Research personnel will include the Core Director, Study Coordinator, Research Outreach Specialist and Clinician. Additional research and administrative personnel will offer support. The team will conduct weekly research team meefings to assure complefion of project 1, 2 and 3 activities. These meetings will have the participation of principal investigators, laboratory staff, clinical and bidnformafics cores. Human subject protecfion and research appropriateness will be monitored by the IRB, our Division Research Task Force and the Youth Community Advisory Board. Our site characterisfics and long history of successful research Implementafion make us uniquely qualified to conduct projects 1, 2 and 3