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中文摘要
翻译
密歇根大学综合癌症中心(UMCCC)前列腺癌孢子管理核心 S负责领导、指导和管理。行政核心负责监督所有方面和 在广泛的孢子范围内执行许多职责。这些职责是:i)提供 科学领导孢子调查人员;2)指导整个孢子的翻译成分 项目;3)作为孢子活动和信息的协调单位;4)监督和 管理所有预算问题和财务;5)维护UMCCC前列腺癌孢子网页;6)提供 所有项目、研究发展、职业发展和核心的行政框架;7) 管理试点项目和种子基金的年度竞争;8)应用成本效益和质量 控制因素;9)促进孢子与大学之间的相互作用;10)促进相互作用 孢子和其他孢子与NCI之间的关系;11)与NCI项目工作人员沟通并 协调提交所需报告;12)召集会议并为会议提供行政支持;13) 监督招募妇女和少数群体;14)确保遵守条例 关于研究中的动物;以及15)协调组织库和数据库之间的质量保证。 肯尼斯·J·皮恩塔,医学博士,密歇根大学综合泌尿外科肿瘤联席主任 癌症中心继续担任行政核心的首席调查员。凯瑟琳·库尼,医学博士, 继续担任行政核心的联席主任。库尼博士负责监督所有的发展 项目以及生物统计学和组织核心。医学博士詹姆斯·蒙蒂继续担任联合导演 通过他的临床指导负责孢子的翻译科学 申请委员会。吉尔·米勒女士自1998年以来一直担任孢子管理员,并将 继续担任这一角色。她已经展示了她管理这一大型研究计划的能力 高效的方式。这一核心提供了框架,以支持UMCCC的成功和使命 孢子作为一个有凝聚力的研究小组,致力于翻译研究的发展 前列腺癌。 这个项目和孢子翻译任务的成功是今年我们的 综合调查团队共同努力,利用孢子资源赢得首届年度AACR 发现TMPRSS重要性的团队科学奖:ETS家族基因融合在 前列腺癌的肿瘤发生。该奖项由美国癌症协会设立 研究(AACR)承认并促进跨学科团队对 了解癌症和/或将研究发现转化为临床癌症应用。
英文摘要
The University of Michigan Comprehensive Cancer Center (UMCCC) Prostate SPORE Administration Core s responsible for leadership, guidance and management. The Administration Core oversees all aspects and performs numerous duties across the expansive scope of the SPORE. These duties are to: i) provide scientific leadership to SPORE investigators; 2) direct the translational components of the overall SPORE program; 3) function as the coordinating unit for SPORE activities and information; 4) oversee and administer all budgetary issues and finances; 5) maintain UMCCC Prostate SPORE web page; 6) provide administrative framework for all projects, research development, career development, and cores; 7) administer the yearly competition for pilot projects and seed grants; 8) apply cost effectiveness and quality control factors; 9) facilitate interactions between the SPORE and the University, 10) facilitate interactions between the SPORE and other SPOREs and the NCI; 11) communicate with NCI program staff and coordinate submission of required reports; 12) convene and provide administrative support for meetings; 13) Drovide oversight for the recruitment of women and minorities; 14) assure compliance with regulations regarding animals in research; and 15) coordinate quality assurance between tissue banks and databases. Kenneth J. Pienta, MD, co-director of urologic oncology for the University of Michigan Comprehensive Cancer Center continues to serve as principal investigator of the Administrative Core. Kathleen Cooney, MD, continues to serve as a co-director of the Administrative Core. Dr. Cooney oversees all of the developmental programs as well as the Biostatistics and Tissue Cores. James Montie, M.D., continues to serve as a codirector responsible for the translational science of the SPORE through his direction of the Clinical Applications Committee. Ms. Jill Miller has filled the role as SPORE administrator since 1998 and will continue in this role. She has demonstrated her ability to administer this large research program in an efficient manner. This core provides the framework to support the success and mission of the UMCCC SPORE as a cohesive group of investigators committed to the development of translational research in prostate cancer. The success of the translational mission of this project and the SPORE was exemplified this year by our integrated team of investigators working together and utilizing SPORE resources to win the 1st annual AACR Team Science Award for the discovery of the importance of the TMPRSS:ETS family gene fusions in prostate cancer tumorigenesis. This Award was established by the American Association for Cancer Research (AACR) to acknowledge and catalyze the growing importance of interdisciplinary teams to the understanding of cancer and/or the translation of research discoveries into clinical cancer applications.
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The Johns Hopkins Physical Sciences Oncology Center
  • 批准号:
    9339630
  • 项目类别:
  • 资助金额:
    $211.84万
  • 财政年份:
    2016
  • 负责人:
    KENNETH J. PIENTA
  • 依托单位:
The Johns Hopkins Physical Sciences Oncology Center
  • 批准号:
    9753736
  • 项目类别:
  • 资助金额:
    $174.51万
  • 财政年份:
    2016
  • 负责人:
    KENNETH J. PIENTA
  • 依托单位:
The JAK2 V617F mutation within B cells and T cells leads to a pro-tumor microenvironment
  • 批准号:
    9903606
  • 项目类别:
  • 资助金额:
    $7.38万
  • 财政年份:
    2016
  • 负责人:
    KENNETH J. PIENTA
  • 依托单位:
The Johns Hopkins Physical Sciences Oncology Center
  • 批准号:
    10016193
  • 项目类别:
  • 资助金额:
    $202.01万
  • 财政年份:
    2016
  • 负责人:
    KENNETH J. PIENTA
  • 依托单位: