GENETICS OF KIDNEYS IN DIABETES STUDY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 GoKinD研究是乔治华盛顿大学、马萨诸塞州波士顿乔斯林糖尿病中心、以及遍布美国和加拿大的另外30个地点，以建立来自大量无关1型糖尿病患者的DNA和临床信息的储存库，以促进来自大量无关1型糖尿病患者的研究，从而促进研究糖尿病肾病的遗传基础 来自科学数据和家庭数据的强有力证据支持人们因糖尿病而患肾病的遗传易感性。 遗传学的最新发展使得寻找这种易感性的基因成为可能。 该项目总共将招募4，300多名参与者。 大约2,000名1型糖尿病患者和大约一半的父母。 我们要求GCRC成为来到费尔维尤大学医学中心的参与者的临床站点。 GCRC将负责采血、随机尿样和物理测量的护理时间。 此外，还需要对血液进行少量处理。 所有样本将由我们的研究人员运送。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The GoKinD Study is a collaborative effort between the George Washington University, DC; Joslin Diabetes Center, Boston, MA; and 30 additional sites throughout the United States and Canada to establish a respository of DNA and clinical information from a large number of unrelated patients with type 1 diabetes in order to facilitate studies from a large number of unrelated patients with type 1 diabetes in order to facilitate studies into the genetic basis of diabetic nephropathy. Strong evidence from scientific data and family data exists to support that there is a genetic susceptibility for people to develop kidney disease due to diabetes. Recent developments in genetics have made it possible to search for the genes responsible for this susceptibility. In total, the project will recruit over 4,300 participants. About 2,000 people with type 1 diabetes and about half of that number's parents. We ask the GCRC to be the clinical site for participants who come to Fairview-University Medical Center. The GCRC would be responsible for nursing time in collecting blood, random urine samples, and physical measures. In addition, minor processing of blood would be needed. All samples would be transported by our research staff.