PREVALENCE OF VITAMIN D DEFICIENCY IN PATIENTS ADMITTED TO REHABILITATION UNIT

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这是一项观察性研究，对象是东牛顿医学中心过渡护理单元康复设施的患者。这项研究的目的是确定维生素D缺乏症，并描述该人群骨质疏松症的程度。维生素D缺乏症是一个慢性问题，见于所有年龄组和各种种族群体。最近，人们认识到维生素D缺乏症是住院和疗养院患者中特别常见的问题。高龄、维生素D摄入不足和居家生活使患者患维生素D缺乏症的风险增加，但其本身不足以预测维生素D缺乏症。维生素D状态对近期因急性疾病或手术住院的患者的健康和福祉很重要。考虑到在过渡期护理单位接受康复治疗的患者人群的性质，我们认为，重要的是要描述该亚组中维生素D缺乏症的患病率。为实现研究目标，将对入组研究的受试者进行抽血（测量25-羟基维生素D [25（OH）D]、甲状旁腺激素、钙、白蛋白、骨钙素、碱性磷酸酶和血清CTX），回答简短问卷，并进行骨密度测定以测量其骨密度。本研究共入组100例受试者。通过这项研究，我们希望提高医学界对康复单位患者维生素D和骨质疏松症状况的认识。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is an observational study of patients admitted to the Transitional Care Unit rehabilitation facility in the East Newton Medical Center. The goal of the study is to determine vitamin D deficiency and to characterize the extent of osteoporosis in this population. Vitamin D deficiency is a chronic problem seen in all age groups and a variety of ethnic groups. Recently, it is recognized that vitamin D deficiency is especially common problem in hospitalized and nursing home patients. Advanced age, inadequate vitamin D intake, and housebound living put patients at increased risk for vitamin D deficiency, but on its own are insufficient to predict vitamin deficiency. Vitamin D status is important for the health and well being of patients after recent hospitalization for an acute illness or surgery. Given the nature of the patient population admitted for rehabilitation at the Transitional Care Unit, we believe that it is important to characterize the prevalence of vitamin D deficiency in this subgroup. To achieve the goals of the study, subjects enrolled in the study will have blood drawn (to measure 25-hydroxyvitamin D [25(OH)D], parathyroid hormone, calcium, albumin, osteocalcin, alkaline phosphatase and serum CTX) answer a short questionnaire and undergo bone densitometry to measure their bone density. A total of 100 subjects will be enrolled in this study. With this study we hope to increase awareness in the medical community of the vitamin D and osteoporosis status of patients in rehabilitation units.