Training Program in Developmental Biology

描述（由申请人提供）：这是一个在发育生物学的前和博士后培训计划的竞争性更新。 拟议的计划包括来自多个学校和大学内的部门的教师，并反映了发育生物学研究和培训，已在宾夕法尼亚州发生在过去十年的重大扩展。 培训经验强调针对胚胎发育的基本机制，使用脊椎动物，无脊椎动物和植物有机体的多样性实验室研究。 它促进了现代遗传，细胞和分子方法在发育研究中的应用。 研究培训领域包括控制细胞谱系确定、分化、迁移、器官发生、细胞衰老、形态发生和模式形成的转录和细胞信号传导机制。 鼓励学员探索临床研究领域，包括癌症和遗传疾病的发展。 在为他们的研究培训做准备时，博士前学生在既定的研究课程中接受正式指导，包括发育生物学的讲座课程和遗传，细胞以及发育机制和疾病的分子方法的高级研讨会。 博士前和博士后学生还参加发育生物学期刊俱乐部，研讨会计划，选定主题的研究讨论组，年度科学研讨会和年度务虚会。 受训人员在地方研讨会和国家会议上介绍他们的研究成果。 该培训计划的主要目标是培养学员在学术和政府机构或生物技术行业的发育生物学领域担任独立调查员。

DESCRIPTION (provided by applicant): This is a competitive renewal for a pre- and post-doctoral training program in developmental biology. The proposed program includes faculty from multiple schools and departments within the University, and reflects a major expansion of developmental biology research and training that has occurred at Pennsylvania over the past ten years. The training experience emphasizes laboratory research directed towards basic mechanisms of embryonic development using a diversity of vertebrate, invertebrate, and plant organisms. It fosters the application of modern genetic, cellular, and molecular approaches to developmental studies. Research training areas include transcription and cell signaling mechanisms that control cell lineage determination, differentiation, migration, organogenesis, cellular senescence, morphogenesis, and pattern formation. Trainees are encouraged to explore clinical research areas including cancer and genetic diseases of development. In preparation for their research training, predoctoral students receive formal instruction in an established curriculum of study, including lecture courses in developmental biology and advanced seminars on genetic, cellular, as well as molecular approaches to developmental mechanisms and disease. Pre- and post-doctoral students also participate in developmental biology journal clubs, a seminar program, research discussion groups on selected topics, annual scientific symposia, and a yearly retreat. Trainees present their research findings at local symposia and national conferences. The primary objective of this training program is to prepare trainees for careers as independent investigators in the field of developmental biology in academic and governmental institutions or in the biotechnology industry.