Pre and Post Doctoral Training: UMKC School of Dentistry

描述(由申请人提供)：本提案是修订后的竞争性续期培训补助金DE07294(11至15年)，是对美国国立牙科和颅面研究所重新发布的PAR-00-116的直接回应，发布日期：2005年5月5日。该提案旨在培养一支高技能、互动的科学家队伍，他们能够成功地应对牙科、口腔和颅面研究中不断扩大的机会。该培训计划在设计上是高度跨学科的，在博士前和博士后培训水平上服务于各种互动学科。由于培训水平的多样性，以及在研究和教育计划中对跨学科和转化/临床的重视，导师和主任处于独特的地位，能够有效和直接地回应计划公告中概述的目标。培训计划的目标是：1)培养牙医科学家进行临床相关的口腔健康研究；2)培养一支多学科的有才华的研究人员队伍，从事牙科和颅面科学；以及3)培养下一代牙科学校的教职员工。培训强调三个主要研究领域，包括：1)骨生物学；2)牙科生物材料(包括生物力学、生物信息学和牙科和颅面生物工程)；3)牙科翻译/临床研究。这些培训和研究工作的增长在过去五年中大大扩大。亮点包括：1)建设1.4万平方米。英国《金融时报》2)外部研究资助增加了三倍，从2001年的150万美元增加到2006年的500多万美元；3)填补的终身教职教员职位从2001年的4个增加到2006年的13个；以及4)从各种来源支助的受训者人数从2001年的15人增加到2006年的52人。每一年的培训将有10至12名牙科暑期研究奖学金学生，由牙科学校资助；10名工程学学生，为期10周，将由“牙科科学研究工程师培训计划”(069501丹麦克朗)资助；3名全日制博士生；5名牙医，攻读跨学科博士学位；以及2名基础科学系和/或牙科系短期实习生。在博士前和博士后培训中，11年级共要求8个全日制职位，12年级9个，13至15年级10个。该提案的一个主要组成部分是对牙医进行足够深入的科学方法培训，使他们能够成为协作、跨学科、合理独立、基础和/或翻译/临床研究人员。

DESCRIPTION (provided by applicant): This proposal is a revised competing renewal of training grant, DE07294 (years 11 through 15), and is in direct response to the reissue of PAR-00-116 from the National Institutes of Dental and Craniofacial Research, release date: May 5, 2005. The proposal is designed to develop a cadre of highly skilled, interactive scientists who can successfully address the expanding opportunities in dental, oral, and craniofacial research. The training program is highly interdisciplinary by design, serving a wide variety of interactive disciplines at pre-doctoral and post-doctoral training levels. Because of the variety of training levels, and the interdisciplinary and translational/clinical emphasis in the research and educational programs, the mentors and the Director are uniquely positioned to respond effectively and directly to the goals outlined in the program announcement. The goals of the training program are to: 1) produce dentist-scientists to conduct clinically relevant oral health research; 2) train a multi-disciplinary cadre of talented investigators for careers in dental and craniofacial science; and 3) develop the next generation of dental school faculty. The training emphasizes three primary research areas which include: 1) bone biology; 2) dental biomaterials (including biomechanics, bioinformatics and dental and craniofacial bioengineering); and 3) dental translational/clinical research. The growth of these training and research efforts has greatly expanded over the past five years. Highlights include: 1) the construction of 14,000 sq. ft. of additional research space was completed and occupied in April, 2004; 2) a threefold increase in outside research funding support from $1.5M in 2001 to over $5.0M in 2006; 3) an increase in filled tenure track faculty positions from 4 in 2001 to 13 in 2006; and 4) an increase in the number of trainees supported from a variety of sources increased from15 in 2001 to 52 in 2006. For each year of training there will be 10 to 12 dental summer research fellowship students supported from dental school funds; 10 engineering students for 10 weeks of training, who will be funded from "Dental Science Research Training Program for Engineers" (DK 069501); three full-time pre-doctoral students; five dentists pursuing interdisciplinary Ph.D. degrees; and two basic science faculty and/or dental faculty short-term trainees. A total of eight full-time appointments are requested for year 11, nine in year 12 and 10 in years 13 through 15 in pre- and post-doctoral training. Two short-term training positions for faculty are requested for years 11 through 15. A main component of the proposal is to train dentists in the scientific method in sufficient depth to enable them to become collaborative, interdisciplinary, reasonably independent, basic, and/or translational/clinical researchers.