CLINICAL RISK FACTORS IN OPTIC NERVE HYPOPLASIA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 视神经发育不良(ONH)是指单侧或双侧视神经先天性发育不良，曾被认为是少见的，但现在被认为是儿童视力不正常的主要原因，也是CHLA先天性失明的主要原因。这项研究旨在提供有关可能在出生前形成ONH的因素的初步数据。它还旨在将这些因素与疾病的严重程度及其相关的医疗条件联系起来。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Optic nerve hypoplasia (ONH), congenital underdevelopment of one or both optic nerves, was once thought to be rare but is now recognized as a major etiology of subnormal vision in children and is a leading cause of congenital blindness at CHLA. This study is designed to provide preliminary data about the factors that may be involved in the formation of ONH prior to birth. It is also designed to correlate those factors with the severity of the disease and its associated medical conditions.