Multidisciplinary Training in Translational Gastrointestinal and Liver Research

描述（由申请人提供）： 这是一份来自哥伦比亚大学的新申请，要求资助消化和肝脏疾病的博士后培训项目。该计划旨在培养医学博士。研究人员成为独立的基础，临床和转化研究人员。美国对翻译研究人员的需求日益增长，以及它们对国家健康的重要性，最近在国家消化疾病委员会的报告中得到了强调。我们的培训计划主要是基于消化和肝脏疾病在哥伦比亚大学的司，但包括一个高度协作和互动的教师（14名高级，7名初级）从许多部门。通过严格的程序招募的学员，主要来自我们的胃肠病学奖学金计划，将被分配到三个轨道之一：（1）基础GI研究;（2）基础肝脏研究;或（3）临床流行病学研究。学员被分配到一个导师与一个特定的研究项目，但也完成了严格的教学计划，包括交叉培训和多学科教育。无论研究重点如何，所有学员都将参加教学计划，以加强他们对生物统计学和临床试验的了解，并获得基础实验室调查的背景。虽然作为一个新的T32计划创建，这个应用程序的目的是巩固和正式化的高度成功的研究培训计划，已经在哥伦比亚大学。哥伦比亚的胃肠病学奖学金计划只招收研究型胃肠病学研究员，目前正在培训基础和临床研究员。蒂莫西·C博士王，PI和该培训计划的主任，多年来一直积极从事年轻基础和临床科学家的导师工作。成立了一个行政人员培训方案咨询委员会和一个外部咨询委员会。该计划与新授予的NIH CTSA和MS/POR培训计划紧密结合。一项加强征聘代表性不足的族裔群体和妇女的方案已经到位。 公共卫生相关性：消化系统和肝脏疾病领域需要更多的研究人员来提高我们对这些疾病的发病机制，预防和治疗的认识。每年约有6000万至7000万美国人受到消化系统疾病的影响，直接成本超过860亿美元。哥伦比亚大学有能力成为这一领域未来研究人员的主要培训中心。

DESCRIPTION (provided by applicant): This is a new application from Columbia University that requests funding for a postdoctoral training program in digestive and liver diseases. This program is designed to train M.D. investigators to become independent basic, clinical and translational researchers. The growing need for translational researchers in the U.S., and their importance to the nation's health, has been recently highlighted in the report by the National Commission on Digestive Diseases. Our training program is primarily based within the Division of Digestive and Liver Diseases at Columbia University but encompasses a highly collaborative and interactive faculty (14 senior, 7 junior) from many departments. Trainees, recruited through a rigorous process, primarily from our gastroenterology fellowship program, will be assigned to one of three tracks: (1) basic Gl research; (2) basic liver research; or (3) clinical epidemiology research. The trainees are assigned to a mentor with a specific research project but also complete a rigorous program of didactic instruction that includes cross training and multidisciplinary education. Regardless of the research focus, all trainees will enroll in didactic programs to strengthen their knowledge of biostatistics and clinical trials and obtain a background in basic laboratory investigation. Although created as a new T32 program, this application is designed to solidify and formalize the highly successful research training program that has already been put in place at Columbia University. The gastroenterology fellowship program at Columbia recruits only research-oriented Gl fellows and is currently training, and has trained, fellows in both basic and clinical tracks. Dr. Timothy C. Wang, PI and Director of this Training program, has been actively engaged as a mentor of young basic and clinical scientists for many years. An Executive Training Program Advisory Committee and an External Advisory Committee have been created. The program is tightly integrated with the newly award NIH CTSA and the MS/POR training program. A program to enhance recruitment of underrepresented ethnic groups and women is in place. PUBLIC HEALTH RELEVANCE: Many more researchers are needed in the field of digestive and liver diseases to advance our knowledge of disease pathogenesis, prevention and treatment of these disorders. Approximately 60 to 70 million Americans are affected each year at by digestive diseases at a cost > $86 billion in direct costs. Columbia University is strongly position to become a leading center in training future researchers in this field.