2009 Spirochetes, Biology of

描述(由申请人提供)： = 注意：此摘要摘自应用程序，未经SRA校对。如果应用程序扫描过程有问题，提取的文本可能不正确或不完整。 = 第九届戈登螺旋体生物学研究会议将于2010年1-2月在加利福尼亚州文图拉举行。螺旋体生物学会议是独一无二的。这是唯一一个正在进行的国际会议，专门讨论所有具有医学重要性和生物相关性的螺旋体的基础研究，螺旋体是一组独特的真细菌。许多螺旋体是病原体，它们会引起多种疾病，包括梅毒、莱姆病、复发性发热、钩端螺旋体病、牙周病、牛的数字皮炎以及猪和人的痢疾。从历史上看，螺旋体一直很难研究。这些细菌往往具有挑剔的营养要求，而且许多细菌还没有在体外成功培养。目前尚不存在对几种螺旋体进行遗传操作和突变分析的方法。研究不同螺旋体的小组之间交流思想的机会是过去会议的最大好处之一，特别是在基因操纵的新技术领域和不断扩大的功能基因组学领域。伯氏疏螺旋体、梅毒螺旋体、齿状螺旋体的遗传进展和基因组序列的可用性以及钩端螺旋体新的测序项目的应用。提供了丰富的新信息。综合起来，这些进展正在被整合到对这些细菌的生理、结构、发病机制和免疫生物学的正在进行的研究中。以前的每一届螺旋体生物学会议都非常成功，得到了与会者的高度评价，建立了新的合作关系，为展示对这些细菌的最新研究提供了一个论坛，并帮助确定了新的研究方向。与以往的会议一样，我们预计2010年会议的出席人数将达到150人，包括教师、研究生、博士后研究员和工业科学家。代表不同研究兴趣、地理位置和资历的广泛科学家将被邀请参加。2010年，将作出特别努力，确保年轻研究人员(研究生、博士后和初级教员)、妇女和代表性不足的少数群体大量出席。口头和海报演示的组织是为了提供许多讨论、思想交流和合作发展的机会。要求国家卫生研究院提供资金，以部分抵消参与者的旅费和登记费，包括但不限于妇女和/或其他少数群体。这次会议将讨论由螺旋体引起的疾病，包括梅毒、莱姆病、回归热、钩端螺旋体病、牙周病、牛的数字皮炎以及猪和人的痢疾。参与者将包括但不限于妇女和/或其他少数群体。

DESCRIPTION (provided by applicant): ================== NOTICE: THIS ABSTRACT WAS EXTRACTED FROM APPLICATION AND HAS NOT BEEN PROOFED BY AN SRA.WHEN THERE ARE PROBLEMS WITH THE APPLICATION SCANNING PROCESS, THE EXTRACTED TEXT MAY BE INCORRECT OR INCOMPLETE. ================== The ninth Gordon Research Conference on the Biology of Spirochetes will be held in January-February 2010 in Ventura, California. The Biology of Spirochetes Conference is unique. This is the only ongoing international meeting devoted to discussions on basic research of all medically important and biologically relevant spirochetes, a unique group of Eubacteria. Many spirochetes are pathogens, and they cause a variety of diseases, including syphilis, Lyme disease, relapsing fever, leptospirosis, periodontal disease, digital dermatitis of cattle, and swine and human dysentery. Historically, spirochetes have been very difficult to study. These bacteria often have fastidious nutritional requirements, and many have yet to be successfully cultured in vitro. Methods for genetic manipulation and mutational analysis of several spirochete species do not exist. The opportunity for exchange of ideas among groups working on different spirochetes has been one of the greatest benefits of past conferences, particularly in the area of new techniques for genetic manipulation and the expanding field of functional genomics. The application of genetic advancements and the availability of genomic sequences for Borrelia burgdorferi, Treponema pallidum, T. denticola, and new sequencing projects in Leptospira spp. are providing a wealth of new information. Combined, these advances are being integrated into ongoing studies on the physiology, structure, pathogenesis, and immunobiology of these bacteria. Each of the previous Biology of Spirochetes conferences has been highly successful, receiving high praise by attendees, forging new collaborations, providing a forum for presenting state-of-the-art research on these bacteria, and helping to set new research directions. As in previous conferences, we expect attendance at the 2010 conference to reach the maximum of 150 faculty, graduate students, postdoctoral fellows, and industrial scientists. A broad spectrum of scientists representing different research interests, geographic locations, and seniority will be invited to attend. For 2010, special efforts will be made to ensure strong attendance of young investigators (graduate students, post-docs, and junior faculty), women, and underrepresented minorities. The oral and poster presentations are organized to provide many opportunities for discussion, the exchange of ideas, and development of collaborations. Funding from the National Institutes of Health is requested to partially offset the travel and registration expenses of the participants, including but not limited to women and/or other minorities. This conference will address diseases caused by spirochetes, including syphilis, Lyme disease, relapsing fever, leptospirosis, periodontal disease, digital dermatitis of cattle, and swine and human dysentery. Participants will include, but not be limited to, women and/or other minorities.