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Pediatric Graft-vs-Host Disease

Pediatric Graft-vs-Host Disease
儿童移植物抗宿主病
批准号：
7969943
负责人：
alan s wayne
金额：
$32.46万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7969943
关键词：
AdolescentAdultAllogenicChildChildhoodChronicDataDevelopmentDiagnosticDiseaseDisease-Free SurvivalGoalsGrowthGuidelinesHematopoietic Stem Cell TransplantationLifeMorbidity - disease rateNatural HistoryOrganPatientsPediatricsPopulationRecurrenceResearchResearch PersonnelStem cell transplantSupportive careTransplantationTransplantation ImmunologyUnited States National Institutes of Healthbench to bedsidechronic graft versus host diseasegraft vs host diseasemortalitynovel therapeuticspreventresponseworking group

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中文摘要
翻译
其主要目标是促进对疾病的病理生物学和自然史的理解。 并开发新的策略来预防和治疗儿科移植物抗宿主病， 患者这是一个与NCI实验移植免疫学合作的项目 分支和多名NIH校内研究者。目前正在开展以下项目/工作： 进行中：1）GVHD的自然史研究; 2） 慢性移植物抗宿主病儿童的体外光疗法; 3） 制定诊断标准和支持性治疗指南; 4）GVHD的新治疗方法
英文摘要
The primary goal is to advance understanding of the pathobiology and natural history of and to develop new strategies to prevent and treat graft-versus-host disease in pediatric patients. This is a collaborative project with the NCI Experimental Transplantation Immunology Branch and multiple NIH Intramural Investigators. The following projects/efforts are currently underway: 1) Natural History Study of GVHD; 2) Bench-to-Bedside Translational Development of Extracorporeal Photophersis for childrenn with chronic GVHD; 3) National Working Groups to Develop Diagnostic Standards and Supportive Care Guidelines; 4) Novel Therapeutics for GVHD
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会议论文
Pediatric Oncology Branch Clinical Care and Education
Experimental Therapeutics of Pediatric Hematopoietic Malignancies
Pediatric Oncology Branch Clinical Care and Education
Pediatric Graft-vs-Host Disease
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